Tylenol w/ codeine no. 3 and Yaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate) and Yaz (drospirenone; ethinyl estradiol). Common drug interactions include deep vein thrombosis among females.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 3 and Yaz. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

On Jul, 15, 2026

78 people who take Tylenol w/ codeine no. 3 and Yaz together, and have interactions are studied.

Tylenol w/ codeine no. 3 and Yaz drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Yaz, by gender? *:

female:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Pain in extremity
Depression
Abdominal pain
Gallbladder disorder
Dyspnoea (difficult or laboured respiration)
General physical health deterioration (weak health status)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pelvic pain

male:

n/a

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Yaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Nausea (feeling of having an urge to vomit)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Injury
Vomiting
Abdominal pain
Abdominal pain upper
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pelvic pain
Cholecystitis chronic (long lasting infection of gallbladder)

20-29:

Biliary colic
Gallbladder injury
Pregnancy on oral contraceptive
Abdominal discomfort
Cholecystitis (infection of gallbladder)
Constipation
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Alopecia (absence of hair from areas of the body)
Flatulence (flatus expelled through the anus)
Iiird nerve paralysis (totally closed eyelid and a down and out deviation of the eye)

30-39:

Pulmonary embolism (blockage of the main artery of the lung)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Emotional distress
Depression
Dyspnoea (difficult or laboured respiration)
Injury
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain in extremity
Asthenia (weakness)
Faecal volume increased
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Insomnia (sleeplessness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Pruritus (severe itching of the skin)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Premenstrual Syndrome: 16 people, 20.51%
Acne (skin problems that cause pimples): 16 people, 20.51%
Migraine (headache): 9 people, 11.54%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 7 people, 8.97%
Stress And Anxiety: 6 people, 7.69%
Menstruation Irregular: 6 people, 7.69%
Heavy Or Prolong Menstrual Bleeding: 6 people, 7.69%
Depression: 6 people, 7.69%
Nausea (feeling of having an urge to vomit): 5 people, 6.41%
Asthma: 5 people, 6.41%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine no. 3 and Yaz?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously