Tylenol w/ codeine no. 3 and Zyprexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate) and Zyprexa (olanzapine). Common drug interactions include electrocardiogram repolarisation abnormality among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 3 and Zyprexa. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.



On Jul, 15, 2026

41 people who take Tylenol w/ codeine no. 3 and Zyprexa together, and have interactions are studied.

Tylenol w/ codeine no. 3 and Zyprexa drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Zyprexa, by gender? *:

female:

  1. Electrocardiogram repolarisation abnormality
  2. Hypotension (abnormally low blood pressure)
  3. Renal failure acute (rapid kidney dysfunction)
  4. Vascular dementia (vascular dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought)
  5. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
  6. Weight increased
  7. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  8. Bone pain
  9. Colonic polyp (extra part of colon tissue grow in intestine)
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

  1. Dyskinesia (abnormality or impairment of voluntary movement)
  2. Weight decreased
  3. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  4. Depressed level of consciousness
  5. Dissociative disorder
  6. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  7. Dysarthria (speech disorder)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Faecal incontinence (a lack of control over passing stool)
  10. Gastrointestinal motility disorder (abnormal intestinal contractions)

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Zyprexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  2. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  3. Central obesity (belly fat)
  4. Chest pain
  5. Diabetes mellitus non-insulin-dependent
  6. Dyspnoea (difficult or laboured respiration)
  7. General physical condition
  8. Headache (pain in head)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Neck pain

40-49:

  1. Type 2 diabetes mellitus
  2. Abdominal pain
  3. Vomiting
  4. Diabetes mellitus inadequate control
  5. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  6. Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
  7. Neuropathy peripheral (surface nerve damage)
  8. Fall
  9. Nausea (feeling of having an urge to vomit)
  10. Pancreatitis acute (sudden inflammation of pancreas)

50-59:

  1. Suicidal ideation
  2. Abnormal behaviour
  3. Aggression
  4. Cardiac failure
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Completed suicide (act of taking one's own life)
  7. Confusion
  8. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  9. Depressed level of consciousness
  10. Dysarthria (speech disorder)

60+:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Gait disturbance
  3. Hypotension (abnormally low blood pressure)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  6. Vascular dementia (vascular dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought)
  7. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
  8. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  9. Bone pain
  10. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 5 people, 12.20%
  2. Depression: 5 people, 12.20%
  3. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 7.32%
  4. Post-Traumatic Stress Disorder: 3 people, 7.32%
  5. Insomnia (sleeplessness): 3 people, 7.32%
  6. High Blood Pressure: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine no. 3 and Zyprexa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tylenol w/ codeine no. 3 and Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine no. 3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tylenol w/ codeine no. 3 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyprexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and olanzapine (the active ingredients of Tylenol w/ codeine no. 3 and Zyprexa, respectively), and Tylenol w/ codeine no. 3 and Zyprexa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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