Tylenol w/ codeine and Daypro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate) and Daypro (oxaprozin). Common drug interactions include myocardial infarction among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine and Daypro. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Daypro?

Daypro has active ingredients of oxaprozin. It is often used in osteoarthritis. eHealthMe is studying from 2,883 Daypro users. Check the latest studies of Daypro.

On Jul, 06, 2026

32 people who take Tylenol w/ codeine and Daypro together, and have interactions are studied.

Tylenol w/ codeine and Daypro drug interactions.

What are the common drug interactions of Tylenol W/ Codeine and Daypro, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Postoperative ileus
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Syphilis (sexually transmitted , chronic bacterial disease caused by the spirochete treponema pallidum)
Appendicitis (inflammation of the appendix)
Blood cholesterol increased
Colitis (inflammation of colon)

male:

Dizziness
Pain in extremity
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Ataxia (loss of full control of bodily movements)
Atelectasis (partial or complete collapse of the lung)
Balanitis candida (inflammation of the glands penis by infection with candida albicans)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cerebellar infarction (impaired blood circulation to cerebellum)

What are the common drug interactions of Tylenol W/ Codeine and Daypro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Depression
Headache (pain in head)
Anxiety
Appendicitis (inflammation of the appendix)
Colitis (inflammation of colon)
Colitis ulcerative (inflammation of colon with ulcer)
Ileitis (inflammation of the ileum)
Inflammatory bowel disease
Intestinal haemorrhage (bleeding from intestine)
Iron deficiency anaemia

30-39:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Coronary artery thrombosis (clot formation in coronary artery)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary oedema (fluid accumulation in the lungs)

40-49:

Abdominal pain
Arrhythmia (irregular heartbeat)
Chest pain
Dizziness
Dyspnoea exertional (breathlessness or shortness of breath)
Facial pain
Groin pain
Intervertebral disc disorder (spinal disc disorder)
Liver fatty (fat deposition of liver)
Muscle strain (an injury to a muscle in which the muscle fibres tear)

50-59:

Oxygen saturation decreased
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal discomfort
Abdominal pain
Actinomyces test positive
Anaphylactic reaction (serious allergic reaction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Ataxia (loss of full control of bodily movements)

60+:

Palpitations (feelings or sensations that your heart is pounding or racing)
Anaemia (lack of blood)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Postoperative ileus
Pulmonary oedema (fluid accumulation in the lungs)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Syphilis (sexually transmitted , chronic bacterial disease caused by the spirochete treponema pallidum)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

What are the existing conditions these people have? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 21.88%
Menopause (end of monthly cycles in women): 7 people, 21.88%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 21.88%
Headache (pain in head): 6 people, 18.75%
Stress And Anxiety: 2 people, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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