Tylenol w/ codeine and Nubain drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate) and Nubain (nalbuphine hydrochloride). Common drug interactions include drug addiction among females and age indeterminate myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine and Nubain. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Nubain?

Nubain has active ingredients of nalbuphine hydrochloride. It is often used in pain. eHealthMe is studying from 1,749 Nubain users. Check the latest studies of Nubain.

On Jul, 04, 2026

13 people who take Tylenol w/ codeine and Nubain together, and have interactions are studied.

Tylenol w/ codeine and Nubain drug interactions.

What are the common drug interactions of Tylenol W/ Codeine and Nubain, by gender? *:

female:

Drug addiction
Vomiting
Chest pain
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Pregnancy
Premature labour
Suicidal ideation
Completed suicide (act of taking one's own life)

male:

Age indeterminate myocardial infarction (age indeterminate heart attack)
Aggression
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery stenosis (narrowing of coronary artery)
Cough
Crepitations (noises are produced by the rubbing of parts one against the other)
Decreased activity

What are the common drug interactions of Tylenol W/ Codeine and Nubain, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Cardiac failure
Chest pain
Drug exposure during pregnancy
Drug ineffective
Dysuria (painful or difficult urination)
Homicidal ideation (thoughts about human killing another human)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Pregnancy

30-39:

Drug addiction
Completed suicide (act of taking one's own life)
Death
Drug abuser
Drug toxicity
Chest pain
Complications of maternal exposure to therapeutic drugs
Dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspnoea (difficult or laboured respiration)

40-49:

Anger
Drug addiction
Feelings of worthlessness
Hostility
Insomnia (sleeplessness)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Suicidal ideation
Weight decreased

50-59:

Age indeterminate myocardial infarction (age indeterminate heart attack)
Aggression
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery stenosis (narrowing of coronary artery)
Cough
Crepitations (noises are produced by the rubbing of parts one against the other)
Decreased activity

60+:

n/a

What are the existing conditions these people have? *

Migraine (headache): 2 people, 15.38%
Headache (pain in head): 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Premature Labor: 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 1 person, 7.69%
Drug Dependence: 1 person, 7.69%
Cough: 1 person, 7.69%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine and Nubain?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously