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Tylenol w/ codeine and Thalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate) and Thalidomide (thalidomide). Common drug interactions include arthralgia among females and coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine and Thalidomide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Thalidomide?

Thalidomide has active ingredients of thalidomide. eHealthMe is studying from 16,473 Thalidomide users. Check the latest studies of Thalidomide.



On Jul, 24, 2026

16 people who take Tylenol w/ codeine and Thalidomide together, and have interactions are studied.

Tylenol w/ codeine and Thalidomide drug interactions.

What are the common drug interactions of Tylenol W/ Codeine and Thalidomide, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Bladder cyst
  4. Blood pressure increased
  5. Bone disorder
  6. Bone pain
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cardiomegaly (increased size of heart than normal)
  9. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  10. Constipation

male:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Death
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Neuropathy peripheral (surface nerve damage)
  5. Oral candidiasis (fungal infection of mouth)
  6. Osteomyelitis (infection of bone)
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Thrombocytopenia (decrease of platelets in blood)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Bone disorder

What are the common drug interactions of Tylenol W/ Codeine and Thalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Abdominal pain
  4. Acute myocardial infarction (acute heart attack)
  5. Anaemia (lack of blood)
  6. Anxiety
  7. Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
  8. Aortic calcification (aortic calcification sign of heart valve disease)
  9. Arteriosclerosis (thickening and hardening of arteries)
  10. Arthralgia (joint pain)

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Bone disorder
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cerebral haemorrhage (bleeding within the brain)
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Cough
  9. Death
  10. Decreased interest

50-59:

  1. Anxiety
  2. Emotional distress
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Bladder cyst
  5. Blood pressure increased
  6. Bone disorder
  7. Bone pain
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Cardiomegaly (increased size of heart than normal)
  10. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)

60+:

n/a

What are the existing conditions these people have? *

  1. Stress And Anxiety: 9 people, 56.25%
  2. Neoplasm Malignant (cancer tumour): 8 people, 50.00%
  3. Depression: 8 people, 50.00%
  4. Multiple Myeloma (cancer of the plasma cells): 6 people, 37.50%
  5. Metastases To Bone (cancer spreads to bone): 5 people, 31.25%
  6. Nuclear Magnetic Resonance Imaging Brain: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine and Thalidomide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tylenol w/ codeine and Thalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Thalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tylenol w/ codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and thalidomide (the active ingredients of Tylenol w/ codeine and Thalidomide, respectively), and Tylenol w/ codeine and Thalidomide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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