Tylenol w/ codeine and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate) and Tracleer (bosentan). Common drug interactions include alanine aminotransferase increased among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine and Tracleer. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 10, 2026

16 people who take Tylenol w/ codeine and Tracleer together, and have interactions are studied.

Tylenol w/ codeine and Tracleer drug interactions.

What are the common drug interactions of Tylenol W/ Codeine and Tracleer, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Death
Drug ineffective
Lower limb fracture
Nausea (feeling of having an urge to vomit)
Acute respiratory failure
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Cardiac failure

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Hodgkin's disease (cancer originating from white blood cells)
Mitral valve incompetence (inefficient heart valve)
Obstruction
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Viral infection

What are the common drug interactions of Tylenol W/ Codeine and Tracleer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Lower limb fracture
Nausea (feeling of having an urge to vomit)

20-29:

n/a

30-39:

Alanine aminotransferase increased
Aspartate aminotransferase increased

40-49:

Hepatitis a antibody positive
Hepatitis acute
Hepatitis c rna positive
Hepatitis viral
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hodgkin's disease (cancer originating from white blood cells)
Mitral valve incompetence (inefficient heart valve)
Obstruction
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Pain in extremity

60+:

Death
Anaemia (lack of blood)
Fluid retention (an abnormal accumulation of fluid in the blood)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 31.25%
Pulmonary Hypertension Primary (increase in blood pressure in the lung artery with no cause): 2 people, 12.50%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 6.25%
Sleep Disorder: 1 person, 6.25%
Pain In Extremity: 1 person, 6.25%
Oedema Peripheral (superficial swelling): 1 person, 6.25%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.25%
Asthma: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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