Tylenol and Depo-testosterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol (acetaminophen) and Depo-testosterone (testosterone cypionate). Common drug interactions include abdominal tenderness among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol and Depo-testosterone. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.

What is Depo-testosterone?

Depo-testosterone has active ingredients of testosterone cypionate. It is often used in low testosterone. eHealthMe is studying from 4,295 Depo-testosterone users. Check the latest studies of Depo-testosterone.

On Aug, 03, 2026

48 people who take Tylenol and Depo-testosterone together, and have interactions are studied.

Tylenol and Depo-testosterone drug interactions.

What are the common drug interactions of Tylenol and Depo-Testosterone, by gender? *:

female:

Abdominal tenderness
Abdominal wall haematoma (abdominal wall blood clotting)
Acanthosis (thickening of the skin)
Adrenal disorder
Ageusia (loss of taste functions of the tongue)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anogenital warts
Anosmia (partial or complete loss of the sense of smell)
Anxiety

male:

Fatigue (feeling of tiredness)
Depression
Hyperplasia (enlargement of an organ or tissue)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Osteopenia (a condition where bone mineral density is lower than normal)
Vomiting
Weight decreased
Abdominal wall haematoma (abdominal wall blood clotting)

What are the common drug interactions of Tylenol and Depo-Testosterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Proteinuria (presence of protein in the urine)
Muscle spasms (muscle contraction)

20-29:

Ageusia (loss of taste functions of the tongue)
Anosmia (partial or complete loss of the sense of smell)
Ill-defined disorder

30-39:

Disease recurrence
Neuropathy peripheral (surface nerve damage)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)

40-49:

Hypoglycaemia (deficiency of glucose in the bloodstream)

50-59:

Abdominal pain
Back pain
Cough
Depression
Hyperplasia (enlargement of an organ or tissue)
Weight decreased
Abdominal wall haematoma (abdominal wall blood clotting)
Adrenal disorder
Anogenital warts
Anxiety

60+:

Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Thyroid disorder (thyroid diseases)
Abdominal discomfort
Abdominal pain
Abdominal tenderness
Abdominal wall haematoma (abdominal wall blood clotting)
Acanthosis (thickening of the skin)
Adrenal disorder
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 16.67%
High Blood Pressure: 8 people, 16.67%
Joint Pain: 5 people, 10.42%
High Blood Cholesterol: 5 people, 10.42%
Depression: 5 people, 10.42%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 8.33%
Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 8.33%
Headache (pain in head): 4 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.33%
Diabetes: 4 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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