Tylenol and Ionamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol (acetaminophen) and Ionamin (phentermine resin complex). Common drug interactions include electrocardiogram abnormal among females and palpitations among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol and Ionamin. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.

What is Ionamin?

Ionamin has active ingredients of phentermine resin complex. It is often used in weight loss. eHealthMe is studying from 2,408 Ionamin users. Check the latest studies of Ionamin.

On Jul, 20, 2026

29 people who take Tylenol and Ionamin together, and have interactions are studied.

What are the common drug interactions of Tylenol and Ionamin, by gender? *:

female:

Electrocardiogram abnormal
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Loss of consciousness
Muscle cramps (painful sensations caused by muscle contraction)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pulmonary oedema (fluid accumulation in the lungs)
Pulmonary valve incompetence
Road traffic accident
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)

male:

Palpitations (feelings or sensations that your heart is pounding or racing)
Aortic valve incompetence
Dyspnoea (difficult or laboured respiration)
Fall
Panic attack
Blood cholesterol increased
Cardiac disorder
Cardiac murmur (an heart sound in valve abnormality)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Tylenol and Ionamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abnormal dreams
Alopecia (absence of hair from areas of the body)
Anxiety
Asthenia (weakness)
Diarrhoea
Nervousness
Sedation
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cardiovascular disorder (heart diseases)
Valvular heart disease (diseases of the heart valves)

40-49:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Drug maladministration
Echocardiogram abnormal
Electrocardiogram abnormal
Fatigue (feeling of tiredness)
Feeling jittery
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Loss of consciousness
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

50-59:

Aortic valve incompetence
Chest pain
Mitral valve incompetence (inefficient heart valve)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Pulmonary hypertension primary (increase in blood pressure in the lung artery with no cause)
Tricuspid valve incompetence (inefficient heart valve)
Valvular heart disease (diseases of the heart valves)
Arrhythmia (irregular heartbeat)
Cardiac failure
Cardiac failure congestive

60+:

Dyspnoea (difficult or laboured respiration)
Mitral valve incompetence (inefficient heart valve)
Fall
Oedema lower limb (fluid collection in tissue of lower leg)
Panic attack
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Arrhythmia (irregular heartbeat)
Blood cholesterol increased
Cardiac disorder

What are the existing conditions these people have? *

Sinus Congestion (blockage of sinus): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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