Tylenol and Maxitrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol (acetaminophen) and Maxitrol (dexamethasone; neomycin sulfate; polymyxin b sulfate). Common drug interactions include scleral thinning among females and head injury among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol and Maxitrol. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.

What is Maxitrol?

Maxitrol has active ingredients of dexamethasone; neomycin sulfate; polymyxin b sulfate. eHealthMe is studying from 986 Maxitrol users. Check the latest studies of Maxitrol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

41 people who take Tylenol and Maxitrol together, and have interactions are studied.

What are the common drug interactions of Tylenol and Maxitrol, by gender? *:

female:

Scleral thinning (getting thin sclera)
Vision blurred
Arthralgia (joint pain)
Burning sensation
Skin burning sensation
Swelling
Abdominal pain upper
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Blindness
Blood pressure increased

male:

Head injury
Dyspnoea (difficult or laboured respiration)
Confusional state
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Emotional disorder
Eosinophil count increased
Eye irritation
Facial bones fracture (bone fracture of face)
Fall

What are the common drug interactions of Tylenol and Maxitrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Acute respiratory distress syndrome
Ascites (accumulation of fluid in the abdominal cavity)
Blood creatinine increased
Blood potassium increased
Chest pain
Cough
Deafness
Drug hypersensitivity
Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)

20-29:

Fall
Grunting (abnormal, short, deep, hoarse sounds in exhalation that often accompany severe chest pain)
Haematoma (collection of blood outside the blood vessels)
Hyperhidrosis (abnormally increased sweating)
Hypoxia (low oxygen in tissues)
Injury
Intentional self-injury
Loss of consciousness
Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

30-39:

Head injury
Aggression
Abnormal behaviour
Agitation (state of anxiety or nervous excitement)
Anger
Bone pain
Brain injury
Bruxism (habitual grinding of the teeth, typically during sleep)
Clavicle fracture
Confusional state

40-49:

Chronic kidney disease

50-59:

Back pain
Conjunctival erosion (removal of conjunctiva)
Constipation
Diarrhoea
Dry eye (lack of adequate tears)
Eye irritation
Eye swelling
Fluid retention (an abnormal accumulation of fluid in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Nasopharyngitis (inflammation of the nasopharynx)

60+:

Diarrhoea
Scleral thinning (getting thin sclera)
Lung carcinoma cell type unspecified stage 0 (the lung cancer has not spread beyond the inner lining of the lung)
Malignant neoplasm progression (cancer tumour came back)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
White blood cell count decreased
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 17.07%
Multiple Myeloma (cancer of the plasma cells): 6 people, 14.63%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 6 people, 14.63%
Type 2 Diabetes: 5 people, 12.20%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 12.20%
Mood Swings (an extreme or rapid change in mood): 4 people, 9.76%
Tension Headache: 3 people, 7.32%
Stable Angina (a constant chest pain): 3 people, 7.32%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 7.32%
Insomnia (sleeplessness): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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