Tylenol and Pazeo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol (acetaminophen) and Pazeo (olopatadine hydrochloride). Common drug interactions include head injury among females and ear infection among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol and Pazeo. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.

What is Pazeo?

Pazeo has active ingredients of olopatadine hydrochloride. eHealthMe is studying from 1,256 Pazeo users. Check the latest studies of Pazeo.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

26 people who take Tylenol and Pazeo together, and have interactions are studied.

What are the common drug interactions of Tylenol and Pazeo, by gender? *:

female:

Head injury
Joint dislocation (a joint position is changed from normal position)
Renal artery fibromuscular dysplasia (a noninflammatory, nonatherosclerotic disorder that leads to arterial stenosis)
Somnolence (a state of near-sleep, a strong desire for sleep)
Carotid artery disease
Coagulopathy (blood's ability to clot is impaired)
Influenza
Infusion site swelling
Laryngitis (inflammation of the larynx)
Malaise (a feeling of general discomfort or uneasiness)

male:

Ear infection
Influenza like illness

What are the common drug interactions of Tylenol and Pazeo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Ear infection
Influenza like illness

20-29:

n/a

30-39:

Drug ineffective
Feeling hot

40-49:

Drug ineffective
Emotional distress

50-59:

Chronic kidney disease
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Muscle atrophy (a decrease in the mass of the muscle)
Pain in extremity
Renal failure (kidney dysfunction)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Concussion (short loss of normal brain function in response to a head injury)
Coagulopathy (blood's ability to clot is impaired)
Influenza
Infusion site swelling
Laryngitis (inflammation of the larynx)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Rash erythematous (redness of the skin)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 19.23%
Immune System Disorder: 4 people, 15.38%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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