Tylenol and Temsirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol (acetaminophen) and Temsirolimus (temsirolimus). Common drug interactions include posterior reversible encephalopathy syndrome among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol and Temsirolimus. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.

What is Temsirolimus?

Temsirolimus has active ingredients of temsirolimus. eHealthMe is studying from 3,573 Temsirolimus users. Check the latest studies of Temsirolimus.

On Jul, 16, 2026

55 people who take Tylenol and Temsirolimus together, and have interactions are studied.

Tylenol and Temsirolimus drug interactions.

What are the common drug interactions of Tylenol and Temsirolimus, by gender? *:

female:

Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Stomatitis (inflammation of mucous membrane of mouth)
Acidosis (build-up of carbon dioxide in the blood)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Respiratory failure (inadequate gas exchange by the respiratory system)
Syncope (loss of consciousness with an inability to maintain postural tone)
Epistaxis (bleed from the nose)
Nausea (feeling of having an urge to vomit)
Abdominal pain

male:

Diarrhoea
Fatigue (feeling of tiredness)
Mouth ulceration (mouth ulcers)
Myalgia (muscle pain)
Osteomyelitis (infection of bone)
Pleural effusion (water on the lungs)
Visual impairment
Weight decreased
Nausea (feeling of having an urge to vomit)
Decreased appetite

What are the common drug interactions of Tylenol and Temsirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Febrile neutropenia (fever with reduced white blood cells)
Stomatitis (inflammation of mucous membrane of mouth)

10-19:

Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Sepsis (a severe blood infection that can lead to organ failure and death)
Stomatitis (inflammation of mucous membrane of mouth)
Acidosis (build-up of carbon dioxide in the blood)
Cardiac arrest
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)

20-29:

n/a

30-39:

Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Nausea (feeling of having an urge to vomit)
Coccydynia (pain in the coccyx or tailbone area)
Unresponsive to stimuli
Dehydration (dryness resulting from the removal of water)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

40-49:

Abasia (inability to walk)
Adrenal gland cancer metastatic (adrenal gland cancer-spread of cancer to other parts of the body)
Anaemia (lack of blood)
Anger
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Blood testosterone decreased
Bone disorder
Bone marrow failure

50-59:

Osteonecrosis of jaw (death of bone of jaw)
Osteoporosis (bones weak and more likely to break)
Pain in extremity
Pancreatic calcification (deposit of calcium salts in pancreas)
Pancreatitis (inflammation of pancreas)
Pleural effusion (water on the lungs)
Pneumonia
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Presyncope
Pruritus (severe itching of the skin)

60+:

Epistaxis (bleed from the nose)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Escherichia sepsis (bacterial infection by escherichia coli)
Fatigue (feeling of tiredness)
Hypophagia (reduced food intake)
Muscular weakness (muscle weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 9 people, 16.36%
Multiple Myeloma (cancer of the plasma cells): 8 people, 14.55%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 14.55%
Bone Density Decreased: 8 people, 14.55%
Nausea (feeling of having an urge to vomit): 7 people, 12.73%
High Blood Pressure: 7 people, 12.73%
B Precursor Type Acute Leukaemia (lymphoid cancer): 7 people, 12.73%
Stress And Anxiety: 6 people, 10.91%
Renal Cell Carcinoma (a kidney cancer): 5 people, 9.09%
Klebsiella Infection: 4 people, 7.27%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol and Temsirolimus?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously