Tylenol and Xofigo drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tylenol (acetaminophen) and Xofigo (radium ra-223 dichloride). Common drug interactions include bone pain among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Tylenol and Xofigo. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Tylenol?
Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.
What is Xofigo?
Xofigo has active ingredients of radium ra-223 dichloride. eHealthMe is studying from 4,948 Xofigo users. Check the latest studies of Xofigo.
15 people who take Tylenol and Xofigo together, and have interactions are studied.

What are the common drug interactions of Tylenol and Xofigo, by gender? *:
female:
- Bone pain
- Constipation
- Disease progression
- Tumour marker increased
male:
- Fatigue (feeling of tiredness)
- Asthenia (weakness)
- Diarrhoea
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Post inflammatory pigmentation change
- Prostatic specific antigen increased
- Bedridden
- Bone pain
- Cough
- Decreased activity
What are the common drug interactions of Tylenol and Xofigo, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Bone pain
- Constipation
- Tumour marker increased
60+:
- Fatigue (feeling of tiredness)
- Asthenia (weakness)
- Peripheral swelling
- Post inflammatory pigmentation change
- Prostatic specific antigen increased
- Back pain
- Bedridden
- Bone pain
- Cough
- Decreased activity
What are the existing conditions these people have? *
- Prostate Cancer: 6 people, 40.00%
- Prostate Cancer Metastatic: 2 people, 13.33%
- Metastases To Bone (cancer spreads to bone): 2 people, 13.33%
- Stress And Anxiety: 1 person, 6.67%
- Prostate Cancer Stage Iv: 1 person, 6.67%
- Nausea And Vomiting: 1 person, 6.67%
- Nausea (feeling of having an urge to vomit): 1 person, 6.67%
- Muscle Spasms (muscle contraction): 1 person, 6.67%
- Insomnia (sleeplessness): 1 person, 6.67%
- Indigestion: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Tylenol and Xofigo?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tylenol and Xofigo:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tylenol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xofigo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tylenol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xofigo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetaminophen and radium ra-223 dichloride (the active ingredients of Tylenol and Xofigo, respectively), and Tylenol and Xofigo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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