Tysabri and Incivek drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tysabri (natalizumab) and Incivek (telaprevir). Common drug interactions include hypoaesthesia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Tysabri and Incivek. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.

What is Incivek?

Incivek has active ingredients of telaprevir. It is often used in hepatitis c. eHealthMe is studying from 15,526 Incivek users. Check the latest studies of Incivek.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

15 people who take Tysabri and Incivek together, and have interactions are studied.

What are the common drug interactions of Tysabri and Incivek, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Balance disorder
Fatigue (feeling of tiredness)
Gait disturbance
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Arthropathy
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Muscular weakness (muscle weakness)

male:

Pyrexia (fever)
Drug ineffective
Dysuria (painful or difficult urination)
Fall
Head injury
Ligament rupture (tear in ligament)
Loss of control of legs
Lymphocytosis (an increase in the number or proportion of lymphocytes in the blood)
Memory impairment
Migraine (headache)

What are the common drug interactions of Tysabri and Incivek, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hypoaesthesia (reduced sense of touch or sensation)
Renal failure (kidney dysfunction)
Fatigue (feeling of tiredness)
Depression
Hepatic steatosis (fatty liver disease)
Mass
Obesity (having too much body fat)
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Pyrexia (fever)
Balance disorder

50-59:

Drug ineffective
Pyrexia (fever)
Adverse event
Alopecia (absence of hair from areas of the body)
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Contusion (a type of hematoma of tissue in which capillaries)
Decreased immune responsiveness
Dysuria (painful or difficult urination)
Fall

60+:

Anaemia macrocytic (a macrocytic class of anaemia)
Ligament rupture (tear in ligament)
Erythema (redness of the skin)
Hypoaesthesia (reduced sense of touch or sensation)
Speech disorder
Lymphocytosis (an increase in the number or proportion of lymphocytes in the blood)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
White blood cell count increased
Acute lymphocytic leukaemia (cancer of the white blood cells)
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
High Blood Cholesterol: 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Drowsiness: 1 person, 6.67%
Discomfort: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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