Tysabri and Selenium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tysabri (natalizumab) and Selenium (selenium). Common drug interactions include gait disturbance among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Tysabri and Selenium. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.

What is Selenium?

Selenium has active ingredients of selenium. It is often used in vitamin supplementation. eHealthMe is studying from 5,314 Selenium users. Check the latest studies of Selenium.



On Jun, 16, 2026

20 people who take Tysabri and Selenium together, and have interactions are studied.

Tysabri and Selenium drug interactions.

What are the common drug interactions of Tysabri and Selenium, by gender? *:

female:

  1. Gait disturbance
  2. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  3. Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)
  4. Anaphylactic reaction (serious allergic reaction)
  5. Blood creatinine increased
  6. Brain injury
  7. Cholecystitis (infection of gallbladder)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Pancreatitis acute (sudden inflammation of pancreas)
  10. Paralysis

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Hepatitis (inflammation of the liver)
  3. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  4. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  5. Rash macular (small, flat red spots)
  6. Therapeutic response unexpected
  7. Weight decreased
  8. Decreased immune responsiveness
  9. Fall
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Tysabri and Selenium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Brain injury

30-39:

n/a

40-49:

  1. Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)

50-59:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Mobility decreased (ability to move is reduced)
  3. Herpes sepsis (whole-body inflammation caused by herpes simplex virus (hsv))
  4. Loss of consciousness
  5. Memory impairment
  6. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  7. Therapeutic response unexpected
  8. Weight decreased
  9. Cholecystitis (infection of gallbladder)
  10. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

60+:

  1. Blood creatinine increased
  2. Fall
  3. Jc virus test positive
  4. Joint swelling
  5. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  6. Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the existing conditions these people have? *

  1. Pain: 9 people, 45.00%
  2. Gait Disturbance: 5 people, 25.00%
  3. Tonic Convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it): 2 people, 10.00%
  4. Nausea (feeling of having an urge to vomit): 2 people, 10.00%
  5. Dizziness: 2 people, 10.00%
  6. Birth Control: 2 people, 10.00%
  7. Weakness: 1 person, 5.00%
  8. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 5.00%
  9. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 5.00%
  10. Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tysabri and Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tysabri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tysabri and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Selenium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on natalizumab and selenium (the active ingredients of Tysabri and Selenium, respectively), and Tysabri and Selenium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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