Tyvaso and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tyvaso (treprostinil sodium) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include constipation among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Tyvaso and Lortab. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Tyvaso?

Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

On Jul, 08, 2026

26 people who take Tyvaso and Lortab together, and have interactions are studied.

What are the common drug interactions of Tyvaso and Lortab, by gender? *:

female:

Constipation
Diarrhoea
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Oedema (fluid collection in tissue)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Vomiting
Cardiac failure
Cardiac failure congestive
Depression
Fluid overload (too much fluid in the blood)

male:

Chest discomfort
Pneumonia
Anxiety
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Injury

What are the common drug interactions of Tyvaso and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain in extremity
Bone pain
Chest pain
Dyspnoea (difficult or laboured respiration)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

40-49:

Headache (pain in head)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Pain in extremity
Constipation
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Haemoglobin decreased
Insomnia (sleeplessness)
Menstrual disorder (disease of menstrual cycle)
Nausea (feeling of having an urge to vomit)

50-59:

Chest discomfort
Pneumonia

60+:

Anxiety
Cardiac failure congestive
Cor pulmonale (enlargement of the right ventricle of the heart)
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disease progression
Fluid retention (an abnormal accumulation of fluid in the blood)
Hallucination (an experience involving the perception of something not present)
Injury
Lymphoedema (localized fluid retention and tissue swelling)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 20 people, 76.92%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 11.54%
Oedema (fluid collection in tissue): 2 people, 7.69%
High Blood Pressure: 2 people, 7.69%
Depression: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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