Uloric and Accupril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uloric (febuxostat) and Accupril (quinapril hydrochloride). Common drug interactions include dehydration among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Uloric and Accupril. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

What is Accupril?

Accupril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,404 Accupril users. Check the latest studies of Accupril.



On Jul, 15, 2026

15 people who take Uloric and Accupril together, and have interactions are studied.

Uloric and Accupril drug interactions.

What are the common drug interactions of Uloric and Accupril, by gender? *:

female:

  1. Dehydration (dryness resulting from the removal of water)
  2. Diarrhoea
  3. Hypotension (abnormally low blood pressure)
  4. Renal failure acute (rapid kidney dysfunction)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Peripheral swelling
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  5. Weight increased
  6. Angina pectoris (chest pain due to ischemia of the heart muscle)
  7. Benign prostatic hyperplasia (benign enlargement of the prostate)
  8. Constipation
  9. Dehydration (dryness resulting from the removal of water)
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Uloric and Accupril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Nausea (feeling of having an urge to vomit)

50-59:

  1. Renal failure (kidney dysfunction)
  2. Renal cyst (kidney cyst)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Benign prostatic hyperplasia (benign enlargement of the prostate)
  6. Constipation
  7. Dehydration (dryness resulting from the removal of water)
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Diarrhoea
  10. Drug ineffective

60+:

  1. Chronic kidney disease
  2. Decreased appetite
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Dehydration (dryness resulting from the removal of water)
  6. Diarrhoea
  7. Hypoacusis (loss of hearing)
  8. Hypotension (abnormally low blood pressure)
  9. Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 40.00%
  2. High Blood Cholesterol: 3 people, 20.00%
  3. Headache (pain in head): 3 people, 20.00%
  4. Gastric Ulcer (stomach ulcer): 3 people, 20.00%
  5. Itching: 3 people, 20.00%
  6. Irritable Bowel Syndrome: 3 people, 20.00%
  7. Inflammation: 3 people, 20.00%
  8. Cardiac Disorder: 2 people, 13.33%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 13.33%
  10. Diabetes: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Uloric and Accupril?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Uloric and Accupril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Uloric:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Accupril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Uloric and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accupril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on febuxostat and quinapril hydrochloride (the active ingredients of Uloric and Accupril, respectively), and Uloric and Accupril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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