Uloric and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uloric (febuxostat) and Acyclovir (acyclovir). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Uloric and Acyclovir. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

25 people who take Uloric and Acyclovir together, and have interactions are studied.

What are the common drug interactions of Uloric and Acyclovir, by gender? *:

female:

Chronic kidney disease
Acute respiratory failure
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Chills (felling of cold)
Dysstasia (difficulty in standing)

male:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Pyrexia (fever)
Adverse event
Blood creatinine increased
Bradycardia (abnormally slow heart action)
Death
Febrile neutropenia (fever with reduced white blood cells)
Full blood count decreased
Headache (pain in head)

What are the common drug interactions of Uloric and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Bone density decreased
Chills (felling of cold)
Depression
Emotional distress
Febrile neutropenia (fever with reduced white blood cells)

60+:

Chronic kidney disease
Pneumonia
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Death
Emotional distress
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Lymphoma (cancer that begins in immune system cells)
Nephropathy (damage to or disease of a kidney)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pain

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 36.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 12.00%
Hiv Infection: 3 people, 12.00%
Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 8.00%
Pain: 2 people, 8.00%
High Blood Pressure: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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