Uloric and Mesalamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Uloric (febuxostat) and Mesalamine (mesalamine). Common drug interactions include blood glucose decreased among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Uloric and Mesalamine. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Uloric?
Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.
What is Mesalamine?
Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.
24 people who take Uloric and Mesalamine together, and have interactions are studied.

What are the common drug interactions of Uloric and Mesalamine, by gender? *:
female:
- Blood glucose decreased
- Blood glucose increased
- Blood pressure fluctuation
- Cardiac disorder
- Cardiac failure
- Fluid imbalance (imbalance of fluid in body in intake and fluid lost)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Respiratory tract infection viral
- Secretion discharge
- Sinusitis (inflammation of sinus)
male:
- Diarrhoea
- Appetite disorder (abnormal eating habits)
- Tonsil cancer
- Abdominal distension
- Abdominal rigidity
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Rectal haemorrhage (bleeding from anus)
- Pneumonia
- Pyrexia (fever)
What are the common drug interactions of Uloric and Mesalamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Blood glucose decreased
- Blood glucose increased
- Blood pressure fluctuation
- Cardiac disorder
- Cardiac failure
- Fluid imbalance (imbalance of fluid in body in intake and fluid lost)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Respiratory tract infection viral
- Secretion discharge
- Arthralgia (joint pain)
60+:
- Appetite disorder (abnormal eating habits)
- Diarrhoea
- Gastrointestinal inflammation (inflammation of stomach and intestine)
- Haematochezia (passage of stools containing blood)
- Haemorrhage (bleeding)
- Nausea (feeling of having an urge to vomit)
- Osteonecrosis (death of bone)
- Osteoporosis (bones weak and more likely to break)
- Pneumonia
- Pyrexia (fever)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 8 people, 33.33%
- Hypersensitivity: 3 people, 12.50%
- Anaemia (lack of blood): 3 people, 12.50%
- Inflammation: 3 people, 12.50%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 12.50%
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 8.33%
- Herpes Zoster: 2 people, 8.33%
- Herpes Virus Infection: 2 people, 8.33%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%
- Fungal Infection: 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Uloric and Mesalamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Uloric (8,067 reports)
- Mesalamine (28,053 reports)
Browse all drug interactions of Uloric and Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Uloric:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Uloric and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mesalamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on febuxostat and mesalamine (the active ingredients of Uloric and Mesalamine, respectively), and Uloric and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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