Uloric and Procardia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uloric (febuxostat) and Procardia (nifedipine). Common drug interactions include insomnia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Uloric and Procardia. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

What is Procardia?

Procardia has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 15,151 Procardia users. Check the latest studies of Procardia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

14 people who take Uloric and Procardia together, and have interactions are studied.

What are the common drug interactions of Uloric and Procardia, by gender? *:

female:

Insomnia (sleeplessness)
Renal failure (kidney dysfunction)
Blood cholesterol increased
Hypersensitivity
Nephrolithiasis (calculi in the kidneys)
Peripheral swelling
Pruritus (severe itching of the skin)
Rash
Renal failure chronic (long lasting kidney dysfunction)
Renal injury (kidney injury)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Uloric and Procardia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Blood cholesterol increased
Nephrolithiasis (calculi in the kidneys)
Chronic kidney disease

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Death
Hypersensitivity
Pruritus (severe itching of the skin)
Rash
Renal failure chronic (long lasting kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 28.57%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
Hyperkalemia (damage to or disease of the kidney): 2 people, 14.29%
Type 2 Diabetes: 1 person, 7.14%
Tetanus (infection of the nervous system with the potentially deadly bacteria): 1 person, 7.14%
Rickets (softening of bones): 1 person, 7.14%
Indigestion: 1 person, 7.14%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 7.14%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 1 person, 7.14%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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