Uloric and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uloric (febuxostat) and Tracleer (bosentan). Common drug interactions include drug hypersensitivity among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Uloric and Tracleer. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 05, 2026

46 people who take Uloric and Tracleer together, and have interactions are studied.

What are the common drug interactions of Uloric and Tracleer, by gender? *:

female:

Drug hypersensitivity
Dyspnoea exertional (breathlessness or shortness of breath)
Femur fracture
Gastroenteritis (inflammation of stomach and intestine)
Memory impairment
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Ocular icterus (presence of jaundice seen in the sclera of the eye)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral swelling
Pneumonia

male:

Anaemia (lack of blood)
Cardiac failure congestive
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Food poisoning (poison in food)
Loss of consciousness
Nasopharyngitis (inflammation of the nasopharynx)
Peripheral swelling
Urinary tract infection
Viral infection

What are the common drug interactions of Uloric and Tracleer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Pain in jaw
Urine output decreased

50-59:

Death
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Death
Vomiting
Dysarthria (speech disorder)
Facial paralysis (loss of function of face muscle)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoaesthesia (reduced sense of touch or sensation)
Pleural effusion (water on the lungs)
Sinus congestion (blockage of sinus)
Arthralgia (joint pain)
Cardiac failure congestive

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 10 people, 21.74%
Cardiac Disorder: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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