Uloric and Tradjenta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uloric (febuxostat) and Tradjenta (linagliptin). Common drug interactions include pulmonary embolism among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Uloric and Tradjenta. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

What is Tradjenta?

Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.

On Jul, 30, 2026

80 people who take Uloric and Tradjenta together, and have interactions are studied.

What are the common drug interactions of Uloric and Tradjenta, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Tendonitis (a condition that causes pain and swelling of tendons)
Angioedema (rapid swelling of the dermis)
Arrhythmia (irregular heartbeat)
Blood glucose increased
Burning sensation
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Diarrhoea

male:

Constipation
Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
Chondropathy (disease of the cartilage)
Death
Emotional distress
Gait disturbance
Muscle atrophy (a decrease in the mass of the muscle)
Nausea (feeling of having an urge to vomit)
Osteoporosis (bones weak and more likely to break)
Pain

What are the common drug interactions of Uloric and Tradjenta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Blood glucose increased
Chronic kidney disease
Fibromyalgia (a long-term condition which causes pain all over the body)
Injection site pain
Pain in extremity

40-49:

n/a

50-59:

Neoplasm progression (growth of tumour)
Pain in extremity
Pancreatitis (inflammation of pancreas)
Platelet count decreased
Pruritus (severe itching of the skin)
Red blood cell count decreased
Stomatitis (inflammation of mucous membrane of mouth)
Vomiting
White blood cell count decreased
Gait disturbance

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Angioedema (rapid swelling of the dermis)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Decreased appetite
Oedema peripheral (superficial swelling)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 25 people, 31.25%
High Blood Pressure: 24 people, 30.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 26.25%
High Blood Cholesterol: 20 people, 25.00%
Type 2 Diabetes: 11 people, 13.75%
Cardiac Disorder: 10 people, 12.50%
Pain: 9 people, 11.25%
Blood Uric Acid Increased: 8 people, 10.00%
Infection: 8 people, 10.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 8 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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