Ultracet and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ultracet (acetaminophen; tramadol hydrochloride) and Keppra (levetiracetam). Common drug interactions include diabetes mellitus among females and ileus among males.

The phase IV clinical study analyzes what interactions people have when they take Ultracet and Keppra. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Ultracet?

Ultracet has active ingredients of acetaminophen; tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 6,351 Ultracet users. Check the latest studies of Ultracet.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 14, 2026

27 people who take Ultracet and Keppra together, and have interactions are studied.

What are the common drug interactions of Ultracet and Keppra, by gender? *:

female:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Vertigo
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

male:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Pneumonia
Confusional state
Death
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Malignant neoplasm progression (cancer tumour came back)
Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Ultracet and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Obesity (having too much body fat)
Type 2 diabetes mellitus

30-39:

Acute respiratory failure
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Drug ineffective
Foot fracture
Headache (pain in head)
Migraine (headache)

40-49:

Abdominal pain
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Non-cardiac chest pain
Renal failure (kidney dysfunction)
Abdominal pain upper
Anaemia (lack of blood)
Anxiety disorder
Arthralgia (joint pain)
Asthenia (weakness)

50-59:

Acquired oesophageal web (structural abnormalities in the oesophagus)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ankle fracture
Arteriosclerosis (thickening and hardening of arteries)
Asthma
Blindness
Blood pressure fluctuation
Breast disorder
Anxiety
Insomnia (sleeplessness)

60+:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Pneumonia
Psoriasis (immune-mediated disease that affects the skin)
Thrombosis (formation of a blood clot inside a blood vessel)
Tooth disorder (tooth disease)
Tooth fracture
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Death
Dental caries

What are the existing conditions these people have? *

Depression: 6 people, 22.22%
Stress And Anxiety: 4 people, 14.81%
Nausea And Vomiting: 3 people, 11.11%
Migraine (headache): 3 people, 11.11%
Intervertebral Disc Degeneration (spinal disc degeneration): 3 people, 11.11%
Dissociative Disorder: 3 people, 11.11%
Hypersensitivity: 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Glossitis (infection of tongue with soreness): 3 people, 11.11%
Headache (pain in head): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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