Uptravi and Atrovent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uptravi (selexipag) and Atrovent (ipratropium bromide). Common drug interactions include haemoglobin decreased among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Uptravi and Atrovent. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Uptravi?

Uptravi has active ingredients of selexipag. eHealthMe is studying from 26,576 Uptravi users. Check the latest studies of Uptravi.

What is Atrovent?

Atrovent has active ingredients of ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 33,210 Atrovent users. Check the latest studies of Atrovent.

On Jul, 21, 2026

46 people who take Uptravi and Atrovent together, and have interactions are studied.

What are the common drug interactions of Uptravi and Atrovent, by gender? *:

female:

Haemoglobin decreased
Confusional state
Arthralgia (joint pain)
Asthenia (weakness)
Dyspnoea exertional (breathlessness or shortness of breath)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Dizziness
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Malaise (a feeling of general discomfort or uneasiness)
Disability

male:

Dyspnoea (difficult or laboured respiration)
Pain
Gout (uric acid crystals building up in the body)
Haematoma (collection of blood outside the blood vessels)
Haemorrhage (bleeding)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)
Influenza
Joint range of motion decreased (disease of joint movement)
Joint swelling

What are the common drug interactions of Uptravi and Atrovent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alopecia (absence of hair from areas of the body)
Dyspnoea exertional (breathlessness or shortness of breath)
Hypotension (abnormally low blood pressure)
Chronic respiratory failure
Palpitations (feelings or sensations that your heart is pounding or racing)
Pulmonary hypertension (increase in blood pressure in the lung artery)

20-29:

Arthralgia (joint pain)
Chest pain
Cough
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Pneumonia
Productive cough

30-39:

Appetite disorder (abnormal eating habits)
Chest pain
Cough
Dyspnoea exertional (breathlessness or shortness of breath)
Hospitalisation
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

Fungal infection
Headache (pain in head)
Pain in jaw
Pyrexia (fever)
Fall
Jaw fracture
Multiple fractures
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood glucose decreased
Blood pressure decreased

50-59:

Brain abscess
Electric shock
Erythema (redness of the skin)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Gout (uric acid crystals building up in the body)
Haematoma (collection of blood outside the blood vessels)
Haemoglobin decreased
Haemorrhage (bleeding)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)

60+:

Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Percutaneous coronary intervention
Stent placement
Acute myocardial infarction (acute heart attack)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Cough
Cardiac arrest
Pneumonia

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 29 people, 63.04%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 22 people, 47.83%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 7 people, 15.22%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 7 people, 15.22%
Dry Eyes (lack of adequate tears): 7 people, 15.22%
Dyslipidaemia (abnormal amount of lipids): 7 people, 15.22%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 7 people, 15.22%
Indigestion: 7 people, 15.22%
Interstitial Lung Disease: 7 people, 15.22%
Infection: 6 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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