Uptravi and Risperdal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Uptravi (selexipag) and Risperdal (risperidone). Common drug interactions include nausea among females and acute right ventricular failure among males.
The phase IV clinical study analyzes what interactions people have when they take Uptravi and Risperdal. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Uptravi?
Uptravi has active ingredients of selexipag. eHealthMe is studying from 26,576 Uptravi users. Check the latest studies of Uptravi.
What is Risperdal?
Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.
15 people who take Uptravi and Risperdal together, and have interactions are studied.

What are the common drug interactions of Uptravi and Risperdal, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Malaise (a feeling of general discomfort or uneasiness)
- Headache (pain in head)
- Myalgia (muscle pain)
- Brain natriuretic peptide increased
- Infusion site induration
- Infusion site infection
- Infusion site pain
- Infusion site swelling
male:
- Acute right ventricular failure (acute heart attack)
- Cough
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hypokalaemia (low potassium)
- Pneumonia
- Pneumonia influenzal (the flu with pneumonia)
- Pyrexia (fever)
- Respiratory tract haemorrhage (respiratory tract bleeding)
- Respiratory tract infection
- Right ventricular failure (right half of the heart fails to work)
What are the common drug interactions of Uptravi and Risperdal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Brain natriuretic peptide increased
- Infusion site induration
- Infusion site infection
- Infusion site pain
- Infusion site swelling
- Pulmonary arterial pressure increased
- Injection site induration
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Blood potassium decreased
- Constipation
- Disease recurrence
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Pulmonary congestion (congestion in the lungs)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Weight decreased
60+:
- Headache (pain in head)
- Myalgia (muscle pain)
- Pyrexia (fever)
- Respiratory tract haemorrhage (respiratory tract bleeding)
- Respiratory tract infection
- Right ventricular failure (right half of the heart fails to work)
- Toothache (tooth pain)
- Acute right ventricular failure (acute heart attack)
- Arthralgia (joint pain)
- Cough
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 80.00%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 20.00%
- Type 2 Diabetes: 2 people, 13.33%
- Right Ventricular Failure (right half of the heart fails to work): 2 people, 13.33%
- Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 13.33%
- Stable Angina (a constant chest pain): 1 person, 6.67%
- Insomnia (sleeplessness): 1 person, 6.67%
- High Blood Pressure: 1 person, 6.67%
- Headache (pain in head): 1 person, 6.67%
- Gastric Ulcer (stomach ulcer): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Uptravi and Risperdal?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Uptravi and Risperdal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Uptravi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Risperdal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Uptravi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Risperdal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on selexipag and risperidone (the active ingredients of Uptravi and Risperdal, respectively), and Uptravi and Risperdal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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