Urocit-k and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Urocit-k (potassium citrate) and Melatonin (melatonin). Common drug interactions include sinusitis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Urocit-k and Melatonin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Urocit-k?

Urocit-k has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 708 Urocit-k users. Check the latest studies of Urocit-k.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

20 people who take Urocit-k and Melatonin together, and have interactions are studied.

Urocit-k and Melatonin drug interactions.

What are the common drug interactions of Urocit-K and Melatonin, by gender? *:

female:

Sinusitis (inflammation of sinus)
Systemic mycosis (fungal infections of the body)
Weight decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Chronic kidney disease
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Cystitis (inflammation of the wall of the bladder)

male:

Fatigue (feeling of tiredness)
Alanine aminotransferase increased
Sinus congestion (blockage of sinus)
Blood electrolytes decreased
Blood potassium decreased
Bradycardia (abnormally slow heart action)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cervical vertebral fracture
Confusional state
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

What are the common drug interactions of Urocit-K and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chronic kidney disease
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Decreased activity
Depression
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)

50-59:

n/a

60+:

Fatigue (feeling of tiredness)
Alanine aminotransferase increased
Weight decreased
Oral fungal infection
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Sinus congestion (blockage of sinus)
Blood electrolytes decreased
Blood potassium decreased
Bradycardia (abnormally slow heart action)
Cervical vertebral fracture

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 40.00%
High Blood Cholesterol: 7 people, 35.00%
Type 2 Diabetes: 5 people, 25.00%
Sleep Disorder: 5 people, 25.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 20.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 20.00%
High Blood Pressure: 4 people, 20.00%
Parkinson's Disease: 3 people, 15.00%
Pain: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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