Ursodeoxycholic acid and Simponi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodeoxycholic acid (ursodiol) and Simponi (golimumab). Common drug interactions include lower gastrointestinal haemorrhage among females and enteritis infectious among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodeoxycholic acid and Simponi. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodeoxycholic acid?

Ursodeoxycholic acid has active ingredients of ursodiol. It is often used in biliary cirrhosis primary. eHealthMe is studying from 7,528 Ursodeoxycholic acid users. Check the latest studies of Ursodeoxycholic acid.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

On Jul, 17, 2026

14 people who take Ursodeoxycholic acid and Simponi together, and have interactions are studied.

Ursodeoxycholic acid and Simponi drug interactions.

What are the common drug interactions of Ursodeoxycholic Acid and Simponi, by gender? *:

female:

Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Toxic skin eruption (skin breakdown due to toxic substance)
Candida sepsis (candida in blood stream)
Sepsis (a severe blood infection that can lead to organ failure and death)
Breast cancer
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Arthralgia (joint pain)
Foot deformity (functional disability of foot)
Urinary tract infection
Abdominal pain

male:

Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Anaemia (lack of blood)
Drug ineffective
Psoriasis (immune-mediated disease that affects the skin)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)

What are the common drug interactions of Ursodeoxycholic Acid and Simponi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)

30-39:

Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)

40-49:

Abdominal pain
Breast cancer
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pyrexia (fever)
Colitis ulcerative (inflammation of colon with ulcer)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Leukopenia (less number of white blood cells in blood)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Toxic skin eruption (skin breakdown due to toxic substance)
Candida sepsis (candida in blood stream)

50-59:

n/a

60+:

Anaemia (lack of blood)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 11 people, 78.57%
Enteritis Infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus): 3 people, 21.43%
Anaemia (lack of blood): 3 people, 21.43%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.14%
Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
Gastritis - Chronic (long lasting inflammation of stomach): 1 person, 7.14%
Cholangitis Sclerosing (infection and obstruction of bile duct): 1 person, 7.14%
Behcet's Syndrome (involves inflammation of the blood vessels): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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