Ursodiol and Amicar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodiol (ursodiol) and Amicar (aminocaproic acid). Common drug interactions include blood bilirubin increased among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodiol and Amicar. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Amicar?

Amicar has active ingredients of aminocaproic acid. eHealthMe is studying from 1,323 Amicar users. Check the latest studies of Amicar.

On Jul, 27, 2026

22 people who take Ursodiol and Amicar together, and have interactions are studied.

What are the common drug interactions of Ursodiol and Amicar, by gender? *:

female:

Blood bilirubin increased
Pleural effusion (water on the lungs)
Abdominal pain
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anal fistula
Anxiety
Atelectasis (partial or complete collapse of the lung)
Blood glucose increased
Blood pressure diastolic decreased
Blood pressure systolic increased

male:

Pyrexia (fever)
Ascites (accumulation of fluid in the abdominal cavity)
Malignant neoplasm progression (cancer tumour came back)
Acute lymphocytic leukaemia (cancer of the white blood cells)
Agitation (state of anxiety or nervous excitement)
Ammonia increased
Apnoea (suspension of external breathing)
Atelectasis (partial or complete collapse of the lung)
Blood glucose increased
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)

What are the common drug interactions of Ursodiol and Amicar, by age (0-1 to 60+)? *:

0-1:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Fear
Injury
Pain
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Stress

2-9:

n/a

10-19:

Transaminases increased
Abdominal distension
Abdominal pain
Anion gap increased
Blood albumin decreased
Blood alkaline phosphatase decreased
Blood calcium decreased
Blood chloride increased
Blood creatinine increased
Blood glucose increased

20-29:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anal fistula
Atelectasis (partial or complete collapse of the lung)
Blood bilirubin increased
Blood glucose increased
Disease recurrence
Febrile neutropenia (fever with reduced white blood cells)
Pleural effusion (water on the lungs)
Renal haemorrhage (bleeding from kidney)
Renal impairment (severely reduced kidney function)

30-39:

Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Anger
Chest pain
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Back pain
Blood glucose increased
Chest discomfort

40-49:

n/a

50-59:

Pneumonia
Pyrexia (fever)
Pulmonary oedema (fluid accumulation in the lungs)
Bradycardia (abnormally slow heart action)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Effusion (an escape of fluid into a body cavity)
Hypotension (abnormally low blood pressure)
Malignant neoplasm progression (cancer tumour came back)
Pleural effusion (water on the lungs)

60+:

Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Hepatic function abnormal

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 22.73%
Cystic Fibrosis (disease of the secretary glands): 3 people, 13.64%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 9.09%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 2 people, 9.09%
Adenovirus Infection: 2 people, 9.09%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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