Ursodiol and Vascepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodiol (ursodiol) and Vascepa (icosapent ethyl). Common drug interactions include arthralgia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodiol and Vascepa. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

On Jul, 16, 2026

21 people who take Ursodiol and Vascepa together, and have interactions are studied.

What are the common drug interactions of Ursodiol and Vascepa, by gender? *:

female:

Arthralgia (joint pain)
Drug ineffective
Eye pain
General physical health deterioration (weak health status)
Headache (pain in head)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Neck pain
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Spinal pain (pain in spine)

male:

Fatigue (feeling of tiredness)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Drug hypersensitivity
Dry mouth
Dyspepsia (indigestion)
Eating disorder
Eosinophil count increased
Excessive masturbation
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

What are the common drug interactions of Ursodiol and Vascepa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Abdominal pain upper
Anxiety
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
Cough
Drug hypersensitivity
Dry mouth
Dyspepsia (indigestion)

40-49:

n/a

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coronary artery bypass
Psoriasis (immune-mediated disease that affects the skin)

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Urticaria (rash of round, red welts on the skin that itch intensely)
Fatigue (feeling of tiredness)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Incisional hernia (hernia caused by an incompletely-healed surgical wound)
Drug hypersensitivity
Eye pain
Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 19.05%
Stress And Anxiety: 3 people, 14.29%
Liver Disorder (liver diseases): 3 people, 14.29%
Depression: 3 people, 14.29%
Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 3 people, 14.29%
Renal Cell Carcinoma (a kidney cancer): 2 people, 9.52%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 9.52%
High Blood Pressure: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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