Valacyclovir hydrochloride and Thalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir hydrochloride (valacyclovir hydrochloride) and Thalidomide (thalidomide). Common drug interactions include immunosuppression among females and photosensitivity reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir hydrochloride and Thalidomide. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

What is Thalidomide?

Thalidomide has active ingredients of thalidomide. eHealthMe is studying from 16,473 Thalidomide users. Check the latest studies of Thalidomide.

On Aug, 05, 2026

96 people who take Valacyclovir hydrochloride and Thalidomide together, and have interactions are studied.

Valacyclovir hydrochloride and Thalidomide drug interactions.

What are the common drug interactions of Valacyclovir Hydrochloride and Thalidomide, by gender? *:

female:

Immunosuppression
Insomnia (sleeplessness)
Jaw disorder (jaw disease)
Lethargy (tiredness)
Leukopenia (less number of white blood cells in blood)
Lichenoid keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin)
Mass
Maternal exposure during pregnancy (use of substance during pregnancy)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mitral valve incompetence (inefficient heart valve)

male:

Photosensitivity reaction
Interstitial lung disease
Diarrhoea
Neuropathy peripheral (surface nerve damage)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Renal failure (kidney dysfunction)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
Left ventricular dysfunction
Bacterial infection

What are the common drug interactions of Valacyclovir Hydrochloride and Thalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Normal newborn
Drug ineffective
Bacterial infection
Constipation
Cough
Influenza
Insomnia (sleeplessness)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)

40-49:

Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
Maternal exposure during pregnancy (use of substance during pregnancy)
Bacterial infection
Erythema (redness of the skin)
Pruritus (severe itching of the skin)

50-59:

Malignant neoplasm progression (cancer tumour came back)
Metastatic malignant melanoma (spreadable cancer tumour of melanine)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Oedema peripheral (superficial swelling)
Pain
Pain in extremity
Plasma cell myeloma (cancer that begins in plasma cells)
Rash morbilliform (a rash that looks like measles)

60+:

Interstitial lung disease
Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Pneumonia
Skin lesion
Abdominal distension
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abscess intestinal (collections of pus-intestinal)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve incompetence

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 83 people, 86.46%
Pain: 17 people, 17.71%
High Blood Pressure: 6 people, 6.25%
Constipation: 6 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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