Valacyclovir hydrochloride and Vesanoid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir hydrochloride (valacyclovir hydrochloride) and Vesanoid (tretinoin). Common drug interactions include agranulocytosis among females and endocarditis among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir hydrochloride and Vesanoid. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

What is Vesanoid?

Vesanoid has active ingredients of tretinoin. eHealthMe is studying from 1,366 Vesanoid users. Check the latest studies of Vesanoid.



On Aug, 02, 2026

38 people who take Valacyclovir hydrochloride and Vesanoid together, and have interactions are studied.

Valacyclovir hydrochloride and Vesanoid drug interactions.

What are the common drug interactions of Valacyclovir Hydrochloride and Vesanoid, by gender? *:

female:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Hepatic failure (liver failure)
  3. Hepatitis (inflammation of the liver)
  4. Lung disorder (lung disease)
  5. Overdose
  6. Respiratory distress (difficulty in breathing)
  7. Transaminases increased

male:

  1. Endocarditis (inflammation in heart muscle)
  2. Extremity necrosis (death of body tissue of arms and legs)
  3. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Diarrhoea
  6. Cerebral venous thrombosis (clot in brains venous blood system)
  7. Jugular vein thrombosis (clot in jugular vein)
  8. Septic embolus (a type of embolism that is infected with bacteria)
  9. Staphylococcal infection (an infection with staphylococcus bacteria)
  10. Tongue ulceration (ulcers on tongue)

What are the common drug interactions of Valacyclovir Hydrochloride and Vesanoid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cerebral venous thrombosis (clot in brains venous blood system)

30-39:

  1. Septic embolus (a type of embolism that is infected with bacteria)
  2. Staphylococcal infection (an infection with staphylococcus bacteria)
  3. Tongue ulceration (ulcers on tongue)
  4. Vasculitis (inflammation of a blood vessel or blood vessels)
  5. Weight increased
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  7. Lung disorder (lung disease)
  8. Overdose
  9. Respiratory distress (difficulty in breathing)
  10. Transaminases increased

40-49:

  1. Hepatic failure (liver failure)
  2. Hepatitis (inflammation of the liver)

50-59:

n/a

60+:

  1. Electrocardiogram qt prolonged
  2. Hypokalaemia (low potassium)
  3. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Diarrhoea

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 32 people, 84.21%
  2. Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 10 people, 26.32%
  3. High Blood Pressure: 8 people, 21.05%
  4. Infection: 6 people, 15.79%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 15.79%
  6. Oedema (fluid collection in tissue): 5 people, 13.16%
  7. Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 5.26%
  8. Stress And Anxiety: 2 people, 5.26%
  9. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 2 people, 5.26%
  10. Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valacyclovir hydrochloride and Vesanoid:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vesanoid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valacyclovir hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vesanoid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride and tretinoin (the active ingredients of Valacyclovir hydrochloride and Vesanoid, respectively), and Valacyclovir hydrochloride and Vesanoid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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