Valacyclovir and Ilevro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir (valacyclovir hydrochloride) and Ilevro (nepafenac). Common drug interactions include renal impairment among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir and Ilevro. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

What is Ilevro?

Ilevro has active ingredients of nepafenac. eHealthMe is studying from 1,531 Ilevro users. Check the latest studies of Ilevro.



On Jul, 21, 2026

14 people who take Valacyclovir and Ilevro together, and have interactions are studied.

Valacyclovir and Ilevro drug interactions.

What are the common drug interactions of Valacyclovir and Ilevro, by gender? *:

female:

  1. Renal impairment (severely reduced kidney function)
  2. Cataract (clouding of the lens inside the eye)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Constipation
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Decreased appetite
  7. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  8. Dyspepsia (indigestion)
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Failure to thrive (inadequate weight gain and physical growth in children)

male:

  1. Death
  2. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Valacyclovir and Ilevro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Decreased activity
  5. Depression
  6. Emotional distress
  7. Pain
  8. Renal failure (kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)
  10. Death

50-59:

n/a

60+:

  1. Anxiety
  2. Cataract (clouding of the lens inside the eye)
  3. Renal injury (kidney injury)
  4. Renal pain (kidney pain)
  5. Sinusitis (inflammation of sinus)
  6. Upper respiratory tract infection
  7. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Depression
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

  1. Cardiac Failure Congestive: 3 people, 21.43%
  2. Infection: 3 people, 21.43%
  3. Multiple Myeloma (cancer of the plasma cells): 3 people, 21.43%
  4. Urination - Painful: 2 people, 14.29%
  5. Oedema (fluid collection in tissue): 2 people, 14.29%
  6. Fever: 2 people, 14.29%
  7. Herpes Zoster: 2 people, 14.29%
  8. High Blood Pressure: 2 people, 14.29%
  9. Blood Uric Acid Increased: 2 people, 14.29%
  10. Constipation: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Valacyclovir and Ilevro?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valacyclovir and Ilevro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valacyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ilevro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valacyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ilevro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride and nepafenac (the active ingredients of Valacyclovir and Ilevro, respectively), and Valacyclovir and Ilevro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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