Valacyclovir and Odefsey drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir (valacyclovir hydrochloride) and Odefsey (emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate). Common drug interactions include fear among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir and Odefsey. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

What is Odefsey?

Odefsey has active ingredients of emtricitabine; rilpivirine hydrochloride; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 4,605 Odefsey users. Check the latest studies of Odefsey.

On Jul, 09, 2026

60 people who take Valacyclovir and Odefsey together, and have interactions are studied.

Valacyclovir and Odefsey drug interactions.

What are the common drug interactions of Valacyclovir and Odefsey, by gender? *:

female:

Fear
Pain in extremity
Bone density decreased
Bone pain
Depressed mood
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Chronic kidney disease
Decreased activity
Heart rate increased
Live birth

male:

Anxiety
Pain
Gait disturbance
Renal impairment (severely reduced kidney function)
Arthralgia (joint pain)
Rib fracture
Wrist fracture
Multiple fractures
Ankle fracture
Dysstasia (difficulty in standing)

What are the common drug interactions of Valacyclovir and Odefsey, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Live birth
Ocular icterus (presence of jaundice seen in the sclera of the eye)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Fatigue (feeling of tiredness)
Glomerulosclerosis (a hardening of the glomerulus in the kidney)
Hypertension (high blood pressure)
Immune system disorder
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

30-39:

Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Gait disturbance
Migraine (headache)
Pain
Penile discharge
Protein total increased

40-49:

Anxiety
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Depression
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Ankle fracture
Arthralgia (joint pain)
Bone density decreased

50-59:

Renal cancer (cancer of kidney)
Renal failure (kidney dysfunction)
Rib fracture
Compression fracture (fracture due to pressure caused by injury)
Decreased appetite
Disturbance in attention
Exercise tolerance decreased
Fracture pain
Gait disturbance
Hand fracture

60+:

Anxiety
Emotional distress
Blood creatinine increased
Fall
Arthralgia (joint pain)
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Multiple fractures
Nightmare (unpleasant dream)
Pain in extremity
Femur fracture

* Approximation only. Some reports may have incomplete information.

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