Valproic acid and Bricanyl drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Valproic acid (valproic acid) and Bricanyl (terbutaline sulfate). Common drug interactions include stevens-johnson syndrome among females.
The phase IV clinical study analyzes what interactions people have when they take Valproic acid and Bricanyl. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Valproic acid?
Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.
What is Bricanyl?
Bricanyl has active ingredients of terbutaline sulfate. It is often used in asthma. eHealthMe is studying from 6,020 Bricanyl users. Check the latest studies of Bricanyl.
25 people who take Valproic acid and Bricanyl together, and have interactions are studied.

What are the common drug interactions of Valproic Acid and Bricanyl, by gender? *:
female:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Agitation (state of anxiety or nervous excitement)
- Head injury
- Headache (pain in head)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anasarca (general swelling, or massive oedema)
- Circulatory collapse
- Coagulopathy (blood's ability to clot is impaired)
- Depression
male:
n/a
What are the common drug interactions of Valproic Acid and Bricanyl, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
40-49:
n/a
50-59:
- Anasarca (general swelling, or massive oedema)
- Circulatory collapse
- Coagulopathy (blood's ability to clot is impaired)
- Oedema peripheral (superficial swelling)
- Phlebitis (inflammation of the walls of a vein)
- Venous thrombosis (blood clot (thrombus) that forms within a vein)
60+:
- Electrocardiogram qt prolonged
- Folate deficiency (lack of folic acid)
- Thrombocytopenia (decrease of platelets in blood)
What are the existing conditions these people have? *
- Vitamin B1 Deficiency: 15 people, 60.00%
- Nausea (feeling of having an urge to vomit): 15 people, 60.00%
- Flatulence (flatus expelled through the anus): 15 people, 60.00%
- Infection: 15 people, 60.00%
- Iron Deficiency: 15 people, 60.00%
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 15 people, 60.00%
- Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 15 people, 60.00%
- Nasopharyngitis (inflammation of the nasopharynx): 15 people, 60.00%
- Constipation: 15 people, 60.00%
- Gallstones (stone formation by bile component): 15 people, 60.00%
* Approximation only. Some reports may have incomplete information.
Do you take Valproic acid and Bricanyl?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Valproic acid (36,193 reports)
- Bricanyl (6,020 reports)
Browse all drug interactions of Valproic acid and Bricanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Valproic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bricanyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valproic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bricanyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on valproic acid and terbutaline sulfate (the active ingredients of Valproic acid and Bricanyl, respectively), and Valproic acid and Bricanyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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