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Valproic acid and Doral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valproic acid (valproic acid) and Doral (quazepam). Common drug interactions include cardio-respiratory arrest among females and cardio-respiratory arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Valproic acid and Doral. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

What is Doral?

Doral has active ingredients of quazepam. eHealthMe is studying from 1,039 Doral users. Check the latest studies of Doral.

On Mar, 18, 2026

12 people who take Valproic acid and Doral together, and have interactions are studied.

Valproic acid and Doral drug interactions.

What are the common drug interactions of Valproic Acid and Doral, by gender? *:

female:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  3. Multiple drug overdose
  4. Postresuscitation encephalopathy
  5. Sepsis (a severe blood infection that can lead to organ failure and death)

male:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Respiratory depression (respiration has a rate below 12 breaths)
  3. Defaecation urgency (a sudden compelling urge to defecate)
  4. Dizziness
  5. Faeces hard
  6. Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
  7. Intestinal obstruction
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia
  10. Body temperature increased

What are the common drug interactions of Valproic Acid and Doral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  3. Dizziness
  4. Faeces hard
  5. Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
  6. Intestinal obstruction
  7. Multiple drug overdose
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia
  10. Pyrexia (fever)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 66.67%
  2. Pneumonia: 8 people, 66.67%
  3. Insomnia (sleeplessness): 8 people, 66.67%
  4. Constipation: 8 people, 66.67%
  5. Stress And Anxiety: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Valproic acid and Doral?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valproic acid and Doral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Doral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valproic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on valproic acid and quazepam (the active ingredients of Valproic acid and Doral, respectively), and Valproic acid and Doral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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