Valproic acid and Ganciclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valproic acid (valproic acid) and Ganciclovir (ganciclovir). Common drug interactions include haemoglobin decreased among females and abdominal sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Valproic acid and Ganciclovir. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

What is Ganciclovir?

Ganciclovir has active ingredients of ganciclovir. eHealthMe is studying from 6,370 Ganciclovir users. Check the latest studies of Ganciclovir.



On Jul, 05, 2026

31 people who take Valproic acid and Ganciclovir together, and have interactions are studied.

Valproic acid and Ganciclovir drug interactions.

What are the common drug interactions of Valproic Acid and Ganciclovir, by gender? *:

female:

  1. Haemoglobin decreased
  2. Platelet count decreased
  3. Drug ineffective
  4. Multiple-drug resistance
  5. Alanine aminotransferase increased
  6. Decreased appetite
  7. Hepatotoxicity (chemical-driven liver damage)
  8. Infection
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Death

male:

  1. Abdominal sepsis (abdominal infection)
  2. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  3. Bacteraemia (presence of bacteria in the blood)
  4. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  5. Cytomegalovirus infection
  6. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Fungaemia (fungi circulate in the blood)
  9. Multiple-drug resistance
  10. Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)

What are the common drug interactions of Valproic Acid and Ganciclovir, by age (0-1 to 60+)? *:

0-1:

  1. Anaemia haemolytic autoimmune (a condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
  2. Coombs test positive
  3. Malaise (a feeling of general discomfort or uneasiness)

2-9:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Multiple-drug resistance
  3. Abdominal pain
  4. Adenovirus infection
  5. Agitation (state of anxiety or nervous excitement)
  6. Amaurosis (partial or total blindness without visible change in the eye)
  7. Aphasia (damage to the parts of the brain that control language)
  8. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  9. Ataxia (loss of full control of bodily movements)
  10. Coma (state of unconsciousness lasting more than six hours)

10-19:

  1. Ammonia increased
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  4. Drug ineffective
  5. Encephalitis (inflammation of the brain)
  6. Encephalitis autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain)
  7. Haemorrhage (bleeding)
  8. Hepatic steatosis (fatty liver disease)
  9. Hepatomegaly (abnormal enlargement of the liver)
  10. Learning disability (difficulty in learning)

20-29:

  1. Circulatory collapse
  2. Hepatic failure (liver failure)
  3. Pyrexia (fever)
  4. Renal failure (kidney dysfunction)

30-39:

  1. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  2. Graft rejection (graft failure)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Blood bilirubin increased
  5. Hepatitis (inflammation of the liver)
  6. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  7. Cytomegalovirus infection
  8. Aspartate aminotransferase increased
  9. Blood amylase increased
  10. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)

40-49:

  1. Haemoglobin decreased
  2. Platelet count decreased
  3. Alanine aminotransferase increased
  4. Decreased appetite
  5. Hepatotoxicity (chemical-driven liver damage)
  6. Infection
  7. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  8. Death
  9. Drug ineffective
  10. Multiple-drug resistance

50-59:

  1. Blood ph increased
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Drug ineffective
  4. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  5. Hypotension (abnormally low blood pressure)
  6. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  7. Platelet disorder
  8. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  9. Abdominal sepsis (abdominal infection)
  10. Punctate keratitis (inflammation of the cornea with tiny spots)

60+:

  1. Bacteraemia (presence of bacteria in the blood)
  2. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  3. Encephalopathy (functioning of the brain is affected by some agent or condition)
  4. Fungaemia (fungi circulate in the blood)
  5. Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)

What are the existing conditions these people have? *

  1. Mydriasis (a dilation of the pupil): 8 people, 25.81%
  2. Keratitis (eye's cornea, the front part of the eye, becomes inflamed): 8 people, 25.81%
  3. Ulcerative Keratitis (ulcerative inflammation of the cornea): 7 people, 22.58%
  4. Conjunctivitis (pink eye): 7 people, 22.58%
  5. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 7 people, 22.58%
  6. Confusion: 5 people, 16.13%
  7. Pneumonia: 5 people, 16.13%
  8. Lymphopenia (an abnormally low level of lymphocytes in the blood): 5 people, 16.13%
  9. Insomnia (sleeplessness): 5 people, 16.13%
  10. Gastric Disorder (disease of stomach): 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valproic acid and Ganciclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ganciclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valproic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ganciclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on valproic acid and ganciclovir (the active ingredients of Valproic acid and Ganciclovir, respectively), and Valproic acid and Ganciclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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