Valsartan and Definity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valsartan (valsartan) and Definity (perflutren). Common drug interactions include back pain among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Valsartan and Definity. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Valsartan?

Valsartan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 63,805 Valsartan users. Check the latest studies of Valsartan.

What is Definity?

Definity has active ingredients of perflutren. eHealthMe is studying from 4,853 Definity users. Check the latest studies of Definity.



On Jul, 17, 2026

24 people who take Valsartan and Definity together, and have interactions are studied.

Valsartan and Definity drug interactions.

What are the common drug interactions of Valsartan and Definity, by gender? *:

female:

  1. Back pain
  2. Muscle spasms (muscle contraction)
  3. Chest pain
  4. Dyspnoea (difficult or laboured respiration)
  5. Cardiac arrest
  6. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  7. Drug hypersensitivity
  8. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  9. Gait disturbance
  10. Hypertensive crisis

male:

  1. Back pain
  2. Muscle spasms (muscle contraction)
  3. Arthralgia (joint pain)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Atrioventricular block complete (heart block complete)
  6. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  7. Cardiac arrest
  8. Chest pain
  9. Death
  10. Dizziness

What are the common drug interactions of Valsartan and Definity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Back pain
  2. Chest pain
  3. Drug hypersensitivity
  4. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  5. Muscle spasms (muscle contraction)
  6. Nausea (feeling of having an urge to vomit)

50-59:

  1. Back pain
  2. Muscle spasms (muscle contraction)
  3. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  4. Pain in extremity
  5. Cardiac arrest
  6. Dizziness
  7. Heart rate increased
  8. Hypertensive crisis
  9. Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
  10. Unresponsive to stimuli

60+:

  1. Back pain
  2. Muscle spasms (muscle contraction)
  3. Arthralgia (joint pain)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Atrioventricular block complete (heart block complete)
  6. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  7. Cardiac arrest
  8. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  9. Death
  10. Gait disturbance

What are the existing conditions these people have? *

  1. Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 8.33%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 8.33%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 8.33%
  4. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.33%
  5. Insomnia (sleeplessness): 2 people, 8.33%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.33%
  7. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 2 people, 8.33%
  8. Fever: 2 people, 8.33%
  9. Dyspnea (difficult or laboured breathing): 2 people, 8.33%
  10. Dyslipidaemia (abnormal amount of lipids): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valsartan and Definity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valsartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Definity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valsartan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Definity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valsartan and perflutren (the active ingredients of Valsartan and Definity, respectively), and Valsartan and Definity (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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