Valsartan and Tecfidera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valsartan (valsartan) and Tecfidera (dimethyl fumarate). Common drug interactions include hepatic encephalopathy among females and gait disturbance among males.

The phase IV clinical study analyzes what interactions people have when they take Valsartan and Tecfidera. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Valsartan?

Valsartan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 63,805 Valsartan users. Check the latest studies of Valsartan.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

99 people who take Valsartan and Tecfidera together, and have interactions are studied.

Valsartan and Tecfidera drug interactions.

What are the common drug interactions of Valsartan and Tecfidera, by gender? *:

female:

Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Mastoiditis (infection of mastoid bone)
Mesenteric vein thrombosis (blood clot in mesenteric vein)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Sepsis (a severe blood infection that can lead to organ failure and death)
Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
Volvulus (obstruction caused by twisting of the stomach or intestine)
Balance disorder

male:

Gait disturbance
Fall
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Hydrocephalus (water on the brain)
Loss of consciousness
Mobility decreased (ability to move is reduced)
Pneumonia
Renal failure (kidney dysfunction)
Cerebral haemorrhage (bleeding within the brain)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)

What are the common drug interactions of Valsartan and Tecfidera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Depression
Gait disturbance
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Limb injury
Muscular weakness (muscle weakness)
Nocturnal dyspnoea (attacks of severe shortness of breath and coughing that generally occur at night)
Pain in extremity

50-59:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Full blood count decreased
Mobility decreased (ability to move is reduced)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscle twitching
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Peroneal nerve palsy
Stress
Therapeutic response unexpected
Tongue biting

60+:

Fall
Asthenia (weakness)
Pneumonia
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Gait disturbance
Hydrocephalus (water on the brain)
Flushing (the warm, red condition of human skin)
Vomiting
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Diarrhoea

What are the existing conditions these people have? *

Gait Disturbance: 20 people, 20.20%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 8 people, 8.08%
Constipation: 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

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