Vancomycin hcl and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Aricept (donepezil hydrochloride). Common drug interactions include mental status changes among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Aricept. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.



On Jul, 08, 2026

11 people who take Vancomycin hcl and Aricept together, and have interactions are studied.

Vancomycin hcl and Aricept drug interactions.

What are the common drug interactions of Vancomycin Hcl and Aricept, by gender? *:

female:

  1. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  2. Metastases to lymph nodes (cancer spreads to lymph node)
  3. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  4. Nausea (feeling of having an urge to vomit)
  5. Neck pain
  6. Oedema peripheral (superficial swelling)
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety disorder due to a general medical condition
  3. Suicidal ideation
  4. Type 2 diabetes mellitus
  5. Death
  6. Aspartate aminotransferase increased
  7. Bacterial test positive
  8. Blood alkaline phosphatase increased
  9. Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
  10. Disseminated intravascular coagulation (systemic activation of blood coagulation)

What are the common drug interactions of Vancomycin Hcl and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Metastases to lymph nodes (cancer spreads to lymph node)
  2. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  3. Nausea (feeling of having an urge to vomit)
  4. Neck pain
  5. Neuropathy peripheral (surface nerve damage)
  6. Oedema peripheral (superficial swelling)
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Osteoporosis (bones weak and more likely to break)

60+:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety disorder due to a general medical condition
  3. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  4. Suicidal ideation
  5. Type 2 diabetes mellitus
  6. Drug eruption (adverse drug reaction of the skin)
  7. Diarrhoea
  8. Drug ineffective
  9. Pyrexia (fever)
  10. Abdominal pain

What are the existing conditions these people have? *

  1. Sleep Disorder: 3 people, 27.27%
  2. Dementia (madness): 3 people, 27.27%
  3. Cerebral Haemorrhage (bleeding within the brain): 2 people, 18.18%
  4. Weight Loss: 1 person, 9.09%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 9.09%
  6. Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
  7. Depression: 1 person, 9.09%
  8. Cardiac Failure Congestive: 1 person, 9.09%
  9. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 1 person, 9.09%
  10. Bone Density Abnormal: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hcl and Aricept:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aricept and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and donepezil hydrochloride (the active ingredients of Vancomycin hcl and Aricept, respectively), and Vancomycin hcl and Aricept (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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