Vancomycin hcl and Cefotaxime sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Cefotaxime sodium (cefotaxime sodium). Common drug interactions include dermatitis bullous among females and brain abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Cefotaxime sodium. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Cefotaxime sodium?

Cefotaxime sodium has active ingredients of cefotaxime sodium. eHealthMe is studying from 2,549 Cefotaxime sodium users. Check the latest studies of Cefotaxime sodium.

On Jul, 15, 2026

13 people who take Vancomycin hcl and Cefotaxime sodium together, and have interactions are studied.

Vancomycin hcl and Cefotaxime sodium drug interactions.

What are the common drug interactions of Vancomycin Hcl and Cefotaxime Sodium, by gender? *:

female:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Myositis (inflammation of the muscles)
Therapeutic response decreased (less preventive response)
Arterial disorder
Blepharitis (chronic inflammation of the eyelid)
Cardiac failure
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Cytomegalovirus infection
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

male:

Brain abscess
Coma (state of unconsciousness lasting more than six hours)
Necrotising colitis (inflammation in the intestines (usually the colon) that can be life-threatening)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Vomiting
Drug resistance (reduction in effectiveness of a drug)
Escherichia infection (bacterial infection by escherichia coli)

What are the common drug interactions of Vancomycin Hcl and Cefotaxime Sodium, by age (0-1 to 60+)? *:

0-1:

Brain abscess
Coma (state of unconsciousness lasting more than six hours)
Drug resistance (reduction in effectiveness of a drug)
Escherichia infection (bacterial infection by escherichia coli)

2-9:

Myositis (inflammation of the muscles)
Therapeutic response decreased (less preventive response)
Cytomegalovirus infection
Multi-organ failure (multisystem organ failure)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

10-19:

n/a

20-29:

Hepatitis (inflammation of the liver)

30-39:

Cardiac failure
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

40-49:

n/a

50-59:

Hyperphagia (an abnormal appetite for food)
Mucosal inflammation (infection of mucous membrane)
Oral candidiasis (fungal infection of mouth)
Ovarian abscess (pus in ovary)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Small intestinal obstruction (blockage in small intestine)
Blepharitis (chronic inflammation of the eyelid)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Haemoglobin decreased

60+:

Arterial disorder
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Rash erythematous (redness of the skin)
Rectal haemorrhage (bleeding from anus)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 15.38%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 7.69%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 7.69%
Sedation: 1 person, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Osteomyelitis (infection of bone): 1 person, 7.69%
Ill-Defined Disorder: 1 person, 7.69%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 7.69%
General Anaesthesia: 1 person, 7.69%
Gastrointestinal Perforation (hole in the digestive tract): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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