Vancomycin hcl and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Compazine (prochlorperazine maleate). Common drug interactions include drug hypersensitivity among females and cystoid macular oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Compazine. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.



On Jul, 07, 2026

23 people who take Vancomycin hcl and Compazine together, and have interactions are studied.

Vancomycin hcl and Compazine drug interactions.

What are the common drug interactions of Vancomycin Hcl and Compazine, by gender? *:

female:

  1. Drug hypersensitivity
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Diarrhoea
  4. Emotional disorder
  5. Fatigue (feeling of tiredness)
  6. Headache (pain in head)
  7. Hypokalaemia (low potassium)
  8. Pruritus (severe itching of the skin)
  9. Rash
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

male:

  1. Cystoid macular oedema (fluid accumulation after cataract surgery)
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Dehydration (dryness resulting from the removal of water)
  6. Drug hypersensitivity
  7. Haemoglobin decreased
  8. Rash
  9. Renal failure (kidney dysfunction)
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Vancomycin Hcl and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Diarrhoea
  2. Emotional disorder
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Hypokalaemia (low potassium)
  6. Pruritus (severe itching of the skin)
  7. Rash

50-59:

  1. Dehydration (dryness resulting from the removal of water)
  2. Haemoglobin decreased
  3. Renal failure (kidney dysfunction)
  4. Weight fluctuation

60+:

  1. Drug hypersensitivity
  2. Cystoid macular oedema (fluid accumulation after cataract surgery)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  5. Disease progression
  6. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  7. Rash
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Hypophysitis (inflammation of the pituitary gland)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 5 people, 21.74%
  2. Diarrhea: 5 people, 21.74%
  3. Pneumonia: 3 people, 13.04%
  4. Pain: 3 people, 13.04%
  5. Insomnia (sleeplessness): 3 people, 13.04%
  6. Rashes (redness): 2 people, 8.70%
  7. Prostate Cancer: 2 people, 8.70%
  8. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
  9. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 8.70%
  10. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hcl and Compazine:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Compazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and prochlorperazine maleate (the active ingredients of Vancomycin hcl and Compazine, respectively), and Vancomycin hcl and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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