Vancomycin hcl and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Senna (senna). Common drug interactions include gastroenteritis viral among females and respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Senna. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

51 people who take Vancomycin hcl and Senna together, and have interactions are studied.

Vancomycin hcl and Senna drug interactions.

What are the common drug interactions of Vancomycin Hcl and Senna, by gender? *:

female:

Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Jaw fracture
Lacrimation increased
Local swelling (swelling at the site of some application of substance or injury)
Loose tooth
Macule (a discoloured spot on the skin)

male:

Respiratory failure (inadequate gas exchange by the respiratory system)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Blood creatinine increased
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Fungaemia (fungi circulate in the blood)
Haemorrhage intracranial (bleeding within the skull)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Liver injury
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)

What are the common drug interactions of Vancomycin Hcl and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hypotension (abnormally low blood pressure)
Renal impairment (severely reduced kidney function)

10-19:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)

20-29:

Heart rate increased
Hypersensitivity
Oxygen saturation decreased
Peripheral swelling
Swelling face
Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

Liver injury
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Hepatitis (inflammation of the liver)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

Dyskinesia (abnormality or impairment of voluntary movement)
Abdominal pain
Abscess (pus)
Acanthoma (a skin cancer)
Alopecia (absence of hair from areas of the body)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain

50-59:

Loss of consciousness
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Mydriasis (a dilation of the pupil)
Oxygen saturation decreased
Pneumonia
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pneumothorax traumatic

60+:

Respiratory failure (inadequate gas exchange by the respiratory system)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Brain natriuretic peptide increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardioactive drug level increased
Chills (felling of cold)
Confusional state
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the existing conditions these people have? *

Pneumonia: 11 people, 21.57%
Stress And Anxiety: 9 people, 17.65%
Pain: 9 people, 17.65%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 15.69%
Nausea (feeling of having an urge to vomit): 8 people, 15.69%
Nausea And Vomiting: 5 people, 9.80%
Thrombocytopenia (decrease of platelets in blood): 4 people, 7.84%
Hypersensitivity: 4 people, 7.84%
Insomnia (sleeplessness): 3 people, 5.88%
Cough: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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