Vancomycin hcl and Sertraline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Sertraline (sertraline hydrochloride). Common drug interactions include ocular hyperaemia among females and nephropathy toxic among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Sertraline. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

On Jul, 16, 2026

50 people who take Vancomycin hcl and Sertraline together, and have interactions are studied.

Vancomycin hcl and Sertraline drug interactions.

What are the common drug interactions of Vancomycin Hcl and Sertraline, by gender? *:

female:

Ocular hyperaemia (an abnormally large amount of blood in eye)
Swelling face
Abdominal discomfort
Abdominal pain
Abscess (pus)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anoxic encephalopathy (brain damage due to lack of oxygen)
Bacterial infection
Cardiac arrest

male:

Nephropathy toxic (damage to kidney due to toxins)
Blood creatinine increased
Epistaxis (bleed from the nose)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Mydriasis (a dilation of the pupil)
Nausea (feeling of having an urge to vomit)
Neurological symptom (symptoms of nervous system disease)
Oxygen saturation decreased
Pain in extremity

What are the common drug interactions of Vancomycin Hcl and Sertraline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Administration site rash
Eye swelling
Injection site pruritus (severe itching at injection site)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Swelling face

20-29:

Hypersensitivity

30-39:

Drug ineffective

40-49:

Abscess (pus)
Anoxic encephalopathy (brain damage due to lack of oxygen)
Bacterial infection
Blood creatinine increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Delirium (wild excitement)
Depressed level of consciousness
Diarrhoea

50-59:

Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Prealbumin decreased
Pruritus (severe itching of the skin)
Psoriasis (immune-mediated disease that affects the skin)
Pyrexia (fever)
Skin exfoliation (removal of the oldest dead skin cells)

60+:

Nephropathy toxic (damage to kidney due to toxins)
Diarrhoea
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood albumin decreased
Depressed mood
Influenza
Injection site pain
Intestinal fistula
Nausea (feeling of having an urge to vomit)
Osteomyelitis (infection of bone)

What are the existing conditions these people have? *

Pain: 10 people, 20.00%
Stress And Anxiety: 5 people, 10.00%
Insomnia (sleeplessness): 4 people, 8.00%
High Blood Pressure: 4 people, 8.00%
Stress Gastritis (swelling (inflammation) and weakening of the stomach lining that occurs during a serious illness): 3 people, 6.00%
Quit Smoking: 3 people, 6.00%
Pneumonia: 3 people, 6.00%
Osteomyelitis (infection of bone): 3 people, 6.00%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.00%
Immunodeficiency Common Variable: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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