Vancomycin hydrochloride and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hydrochloride (vancomycin hydrochloride) and Codeine (codeine sulfate). Common drug interactions include injection site bruising among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hydrochloride and Codeine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hydrochloride?

Vancomycin hydrochloride has active ingredients of vancomycin hydrochloride. It is often used in mrsa infection. eHealthMe is studying from 8,399 Vancomycin hydrochloride users. Check the latest studies of Vancomycin hydrochloride.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.



On Jul, 07, 2026

20 people who take Vancomycin hydrochloride and Codeine together, and have interactions are studied.

Vancomycin hydrochloride and Codeine drug interactions.

What are the common drug interactions of Vancomycin Hydrochloride and Codeine, by gender? *:

female:

  1. Injection site bruising
  2. Lip swelling
  3. Lung disorder (lung disease)
  4. Mitral valve prolapse (heart's mitral valve doesn't work well)
  5. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  6. Oral pain
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Platelet count decreased
  9. Platelet count increased
  10. Pruritus (severe itching of the skin)

male:

  1. Abdominal pain
  2. Diarrhoea
  3. Blood uric acid decreased
  4. Blood uric acid increased
  5. Bone disorder
  6. Cardiac failure
  7. Chronic kidney disease
  8. Clavicle fracture
  9. Constipation
  10. Creatinine urine increased

What are the common drug interactions of Vancomycin Hydrochloride and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Blood osmolarity increased
  2. Blood potassium decreased
  3. Blood urea decreased
  4. Blood urea increased
  5. Blood uric acid decreased
  6. Blood uric acid increased
  7. Creatinine urine increased
  8. Inappropriate antidiuretic hormone secretion
  9. Urine chloride decreased

20-29:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  2. Blood alkaline phosphatase increased
  3. Blood creatinine increased
  4. Gamma-glutamyltransferase increased
  5. Hepatic enzyme increased

30-39:

n/a

40-49:

  1. Pyrexia (fever)
  2. Renal failure (kidney dysfunction)
  3. Platelet count decreased
  4. Abdominal pain
  5. Alanine aminotransferase increased
  6. Appendicitis (inflammation of the appendix)
  7. Cardiac failure
  8. Chronic kidney disease
  9. Decreased appetite
  10. Diarrhoea

50-59:

  1. Drug ineffective
  2. Fatigue (feeling of tiredness)
  3. Pyrexia (fever)
  4. Rash
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Weight decreased
  7. Abdominal pain
  8. Acne (skin problems that cause pimples)
  9. Affective disorder (mental disorder)
  10. Allergy to vaccine

60+:

  1. Diarrhoea
  2. Salmonellosis (an infection with salmonella bacteria)
  3. Clavicle fracture
  4. Defaecation urgency (a sudden compelling urge to defecate)
  5. Intestinal ulcer
  6. Small intestinal obstruction (blockage in small intestine)
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Weight decreased

What are the existing conditions these people have? *

  1. Depression: 3 people, 15.00%
  2. Hypotension (abnormally low blood pressure): 2 people, 10.00%
  3. Nausea (feeling of having an urge to vomit): 2 people, 10.00%
  4. Essential Hypertension (primary hypertension): 2 people, 10.00%
  5. Extubation: 2 people, 10.00%
  6. Gestational Diabetes (diabetes in pregnancy): 2 people, 10.00%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 10.00%
  8. Hypokalemia (low potassium): 2 people, 10.00%
  9. Colitis (inflammation of colon): 2 people, 10.00%
  10. Mucosal Inflammation (infection of mucous membrane): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Vancomycin hydrochloride and Codeine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hydrochloride and Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and codeine sulfate (the active ingredients of Vancomycin hydrochloride and Codeine, respectively), and Vancomycin hydrochloride and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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