Vancomycin hydrochloride and Pentasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hydrochloride (vancomycin hydrochloride) and Pentasa (mesalamine). Common drug interactions include proctalgia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hydrochloride and Pentasa. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hydrochloride?

Vancomycin hydrochloride has active ingredients of vancomycin hydrochloride. It is often used in mrsa infection. eHealthMe is studying from 8,399 Vancomycin hydrochloride users. Check the latest studies of Vancomycin hydrochloride.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.



On Jul, 06, 2026

37 people who take Vancomycin hydrochloride and Pentasa together, and have interactions are studied.

Vancomycin hydrochloride and Pentasa drug interactions.

What are the common drug interactions of Vancomycin Hydrochloride and Pentasa, by gender? *:

female:

  1. Proctalgia (pain in the rectum)
  2. Productive cough
  3. Red blood cell sedimentation rate increased
  4. Respiratory tract congestion (blockage on respiratory system)
  5. Sinusitis (inflammation of sinus)
  6. Stress
  7. Urinary tract infection
  8. Vaginal abscess
  9. Vaginal infection
  10. Vitamin d increased

male:

  1. Pyrexia (fever)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Platelet count decreased
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  6. Upper respiratory tract inflammation
  7. White blood cell count decreased
  8. Hepatic failure (liver failure)
  9. Renal impairment (severely reduced kidney function)
  10. Abdominal pain

What are the common drug interactions of Vancomycin Hydrochloride and Pentasa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Infusion related reaction

20-29:

  1. Abdominal pain
  2. Anal fissure
  3. Dizziness
  4. Drug ineffective
  5. Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

  1. Upper respiratory tract inflammation
  2. Blood pressure decreased
  3. Drug hypersensitivity
  4. Eye swelling
  5. Lip swelling
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Wheezing (a high-pitched whistling sound made while you breath)
  8. Anal abscess

40-49:

n/a

50-59:

  1. Vitamin d increased
  2. White blood cell disorder
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Abdominal pain
  5. Drug ineffective
  6. Acne (skin problems that cause pimples)
  7. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  8. Affective disorder (mental disorder)
  9. Anal fistula
  10. Aphthous ulcer (mouth ulcer)

60+:

  1. Pyrexia (fever)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Bacteraemia (presence of bacteria in the blood)
  4. Bile duct cancer recurrent
  5. Blindness unilateral
  6. Blood creatinine increased
  7. Blood urea increased
  8. Clavicle fracture
  9. Cytomegalovirus enterocolitis (virus infection of intestine and colon)
  10. Cytomegalovirus infection

What are the existing conditions these people have? *

  1. Pain: 12 people, 32.43%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 10 people, 27.03%
  3. Device Related Infection: 7 people, 18.92%
  4. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 10.81%
  5. Infection: 4 people, 10.81%
  6. Back Pain: 3 people, 8.11%
  7. Cytomegalovirus Infection: 3 people, 8.11%
  8. Upper Respiratory Tract Inflammation: 2 people, 5.41%
  9. Gastritis (inflammation of stomach): 2 people, 5.41%
  10. Constipation: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Vancomycin hydrochloride and Pentasa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hydrochloride and Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pentasa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and mesalamine (the active ingredients of Vancomycin hydrochloride and Pentasa, respectively), and Vancomycin hydrochloride and Pentasa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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