Vancomycin and Efudex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin (vancomycin) and Efudex (fluorouracil). Common drug interactions include cough among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin and Efudex. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

What is Efudex?

Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.



On Jul, 11, 2026

13 people who take Vancomycin and Efudex together, and have interactions are studied.

Vancomycin and Efudex drug interactions.

What are the common drug interactions of Vancomycin and Efudex, by gender? *:

female:

  1. Cough
  2. Decreased appetite
  3. Dyspnoea (difficult or laboured respiration)
  4. Lower respiratory tract infection
  5. Pyrexia (fever)
  6. Sinusitis (inflammation of sinus)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Blood pressure systolic increased
  9. Depression
  10. Diarrhoea

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Osteoporosis (bones weak and more likely to break)
  5. Pain
  6. Renal failure (kidney dysfunction)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Bone density decreased
  9. Bone loss
  10. Emotional distress

What are the common drug interactions of Vancomycin and Efudex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Bone density decreased
  5. Bone loss
  6. Emotional distress
  7. Hydronephrosis (water inside the kidney)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Osteonecrosis (death of bone)

50-59:

n/a

60+:

  1. Cough
  2. Decreased appetite
  3. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  4. Erythema (redness of the skin)
  5. Fatigue (feeling of tiredness)
  6. Head discomfort
  7. Headache (pain in head)
  8. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  9. Myalgia (muscle pain)
  10. Pain

What are the existing conditions these people have? *

  1. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 9 people, 69.23%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 69.23%
  3. Bipolar Disorder (mood disorder): 2 people, 15.38%
  4. Hiv Infection: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Vancomycin and Efudex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin and Efudex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Efudex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Efudex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin and fluorouracil (the active ingredients of Vancomycin and Efudex, respectively), and Vancomycin and Efudex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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