Vancomycin and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin (vancomycin) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include pain in extremity among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin and Hydrocodone. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

On Jul, 06, 2026

71 people who take Vancomycin and Hydrocodone together, and have interactions are studied.

Vancomycin and Hydrocodone drug interactions.

What are the common drug interactions of Vancomycin and Hydrocodone, by gender? *:

female:

Pain in extremity
Post procedural swelling
Rash erythematous (redness of the skin)
Anxiety
Cellulitis (infection under the skin)
Fall
Nephrogenic anaemia (anaemia due to kidney disease)
Drug hypersensitivity
Hypoglycaemia (deficiency of glucose in the bloodstream)
Acute respiratory failure

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal impairment (severely reduced kidney function)
Anal abscess
Injury
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bladder dysfunction

What are the common drug interactions of Vancomycin and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug level increased
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Loss of employment
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Quality of life decreased
Renal failure (kidney dysfunction)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anxiety
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fibromyalgia (a long-term condition which causes pain all over the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Dyspnoea (difficult or laboured respiration)
Respiratory distress (difficulty in breathing)
Upper respiratory tract infection
Actinic keratosis (skin disease due to sun exposure)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

50-59:

Nephrogenic anaemia (anaemia due to kidney disease)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Perineal abscess
Subcutaneous abscess
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Genital abscess (build up of pus in genital)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Iga nephropathy (kidney disease- condition prevents the kidneys from filtering waste)

60+:

Chronic kidney disease
Cardiac failure congestive
Bladder dysfunction
Blood viscosity increased
Cellulitis (infection under the skin)
Compression fracture (fracture due to pressure caused by injury)
Erectile dysfunction
Metastatic carcinoma of the bladder (cancer types can spread to the bladder from other place)
Nephrogenic anaemia (anaemia due to kidney disease)
Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 28 people, 39.44%
Pain: 25 people, 35.21%
High Blood Pressure: 21 people, 29.58%
Hiv Infection: 12 people, 16.90%
Depression: 11 people, 15.49%
Weight Decreased: 10 people, 14.08%
Type 2 Diabetes: 10 people, 14.08%
Infection: 10 people, 14.08%
Hypotension (abnormally low blood pressure): 10 people, 14.08%
Stress And Anxiety: 9 people, 12.68%

* Approximation only. Some reports may have incomplete information.

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