Vancomycin and Macrobid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin (vancomycin) and Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline). Common drug interactions include renal failure among females and anal abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin and Macrobid. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

What is Macrobid?

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 9,215 Macrobid users. Check the latest studies of Macrobid.

On Mar, 31, 2026

15 people who take Vancomycin and Macrobid together, and have interactions are studied.

Vancomycin and Macrobid drug interactions.

What are the common drug interactions of Vancomycin and Macrobid, by gender? *:

female:

Renal failure (kidney dysfunction)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Dehydration (dryness resulting from the removal of water)

male:

Anal abscess
Cellulitis (infection under the skin)
Death
Genital abscess (build up of pus in genital)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Scrotal abscess (pus in scrotum)
Scrotal oedema (swelling of scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Testicular necrosis (damaged testes)

What are the common drug interactions of Vancomycin and Macrobid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Chronic kidney disease
Anal abscess
Cellulitis (infection under the skin)

40-49:

Chronic kidney disease
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dizziness
Hyperhidrosis (abnormally increased sweating)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Vomiting

50-59:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

60+:

Hypertension (high blood pressure)
Pneumonia
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Death

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 60.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 46.67%
Stress And Anxiety: 6 people, 40.00%
Sleep Disorder: 6 people, 40.00%
Pain: 6 people, 40.00%
Itching: 5 people, 33.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 26.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 20.00%
Asthma: 3 people, 20.00%
Hypersensitivity: 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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