Vancomycin and Xospata drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin (vancomycin) and Xospata (gilteritinib). Common drug interactions include febrile neutropenia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin and Xospata. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

What is Xospata?

Xospata has active ingredients of gilteritinib. eHealthMe is studying from 2,411 Xospata users. Check the latest studies of Xospata.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

33 people who take Vancomycin and Xospata together, and have interactions are studied.

Vancomycin and Xospata drug interactions.

What are the common drug interactions of Vancomycin and Xospata, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Pain in extremity
Electrocardiogram qt prolonged
Pyrexia (fever)
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gingival bleeding (bleeding gums)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia fungal

male:

Pyrexia (fever)
Bacterial infection
Stomatitis (inflammation of mucous membrane of mouth)
Infection
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Mycobacterial infection
Myelosuppression (a decrease in the production of blood cells)
Neutropenia (an abnormally low number of neutrophils)
Pneumonia
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)

What are the common drug interactions of Vancomycin and Xospata, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pain in extremity
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Epistaxis (bleed from the nose)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gingival bleeding (bleeding gums)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia fungal
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Bacterial infection

20-29:

n/a

30-39:

Febrile neutropenia (fever with reduced white blood cells)
Meningitis pneumococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Pneumococcal bacteraemia (infection confirmed by the isolation of streptococcus pneumoniae)
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Otitis media (inflammation of the middle ear)

40-49:

Pyrexia (fever)
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood pressure decreased
Cardiac failure
Chills (felling of cold)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Eye swelling
Febrile neutropenia (fever with reduced white blood cells)

50-59:

Blood bilirubin increased
Cerebellar infarction (impaired blood circulation to cerebellum)
Electrocardiogram qt prolonged
Febrile neutropenia (fever with reduced white blood cells)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Rash
Drug eruption (adverse drug reaction of the skin)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Neutropenia (an abnormally low number of neutrophils)

60+:

Pyrexia (fever)
Platelet count decreased
Rectal abscess (pus in rectum)
Small intestinal obstruction (blockage in small intestine)
Tumour associated fever (fever because of tumour)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Blood creatine phosphokinase increased
Febrile neutropenia (fever with reduced white blood cells)
Septic shock (shock due to blood infection)
Anal abscess

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 16 people, 48.48%
Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 15 people, 45.45%
Febrile Neutropenia (fever with reduced white blood cells): 12 people, 36.36%
Fever: 11 people, 33.33%
Nausea (feeling of having an urge to vomit): 4 people, 12.12%
Acute Febrile Neutrophilic Dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender): 3 people, 9.09%
Pain: 3 people, 9.09%
Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 3 people, 9.09%
Enterococcal Infection: 3 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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