Vascepa and Lopressor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vascepa (icosapent ethyl) and Lopressor (metoprolol tartrate). Common drug interactions include pleural effusion among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Vascepa and Lopressor. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.



On Jul, 14, 2026

22 people who take Vascepa and Lopressor together, and have interactions are studied.

Vascepa and Lopressor drug interactions.

What are the common drug interactions of Vascepa and Lopressor, by gender? *:

female:

  1. Pleural effusion (water on the lungs)
  2. Septic shock (shock due to blood infection)
  3. Nausea (feeling of having an urge to vomit)
  4. Acute respiratory distress syndrome
  5. Acute respiratory failure
  6. Adenovirus infection
  7. Arthralgia (joint pain)
  8. Blood sodium decreased
  9. Brain natriuretic peptide increased
  10. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)

male:

  1. Acute respiratory failure
  2. White blood cell count decreased
  3. Rash pruritic (redness with itching)
  4. Platelet count decreased
  5. Diarrhoea
  6. Hand-foot-and-mouth disease
  7. Cardiac failure
  8. Dysuria (painful or difficult urination)
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Pain

What are the common drug interactions of Vascepa and Lopressor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Acute respiratory failure
  2. White blood cell count decreased
  3. Death
  4. Decreased appetite
  5. Diarrhoea
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  7. Dysuria (painful or difficult urination)
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Hyperkalaemia (damage to or disease of the kidney)

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 6 people, 27.27%
  2. Type 2 Diabetes: 5 people, 22.73%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 22.73%
  4. Constipation: 5 people, 22.73%
  5. Diarrhea: 5 people, 22.73%
  6. Enlarged Prostate: 5 people, 22.73%
  7. Febrile Neutropenia (fever with reduced white blood cells): 5 people, 22.73%
  8. Nausea (feeling of having an urge to vomit): 5 people, 22.73%
  9. Nausea And Vomiting: 5 people, 22.73%
  10. Pain: 5 people, 22.73%

* Approximation only. Some reports may have incomplete information.

Do you take Vascepa and Lopressor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vascepa and Lopressor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vascepa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lopressor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vascepa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lopressor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on icosapent ethyl and metoprolol tartrate (the active ingredients of Vascepa and Lopressor, respectively), and Vascepa and Lopressor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: