Vasotec and Enablex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vasotec (enalapril maleate) and Enablex (darifenacin hydrobromide). Common drug interactions include calculus ureteric among females and acute prerenal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Vasotec and Enablex. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Vasotec?
Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.
What is Enablex?
Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.
17 people who take Vasotec and Enablex together, and have interactions are studied.

What are the common drug interactions of Vasotec and Enablex, by gender? *:
female:
- Calculus ureteric (stone in ureter)
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
- Carotid artery disease
- Carotid artery stenosis (narrowing of carotid artery)
- Cataract (clouding of the lens inside the eye)
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebral haemorrhage (bleeding within the brain)
- Chest pain
- Confusional state
male:
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anaemia (lack of blood)
- Cardiac failure congestive
- Carotid artery disease
- Cerebral haemorrhage (bleeding within the brain)
- Compression fracture (fracture due to pressure caused by injury)
- Constipation
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Delusion (a false belief or opinion)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
What are the common drug interactions of Vasotec and Enablex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Ill-defined disorder
- Type 2 diabetes mellitus
- Depression
- Suicide attempt
40-49:
- Cataract (clouding of the lens inside the eye)
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebral haemorrhage (bleeding within the brain)
- Chest pain
- Confusional state
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Deafness bilateral
- Death
- Decreased appetite
50-59:
n/a
60+:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Peripheral vascular disorder
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Back pain
- Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)
- Brain injury
- Cardiac failure congestive
- Carotid artery disease
- Cerebral haemorrhage (bleeding within the brain)
What are the existing conditions these people have? *
- Incontinence (lack of moderation or self-control): 6 people, 35.29%
- Diabetes: 6 people, 35.29%
- Birth Control: 6 people, 35.29%
- Pain: 4 people, 23.53%
- Type 2 Diabetes: 3 people, 17.65%
- Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 2 people, 11.76%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 11.76%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
- Joint Pain: 2 people, 11.76%
- Insomnia (sleeplessness): 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Vasotec and Enablex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vasotec and Enablex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vasotec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Enablex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vasotec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Enablex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on enalapril maleate and darifenacin hydrobromide (the active ingredients of Vasotec and Enablex, respectively), and Vasotec and Enablex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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